The CTSA funding to the Michigan Institute for Clinical and Health Research (MICHR) in 2007 marked the beginning of a transformation of clinical-translational research (CTR) at the University of Michigan (UM). This award, coupled with strong institutional support and growing faculty engagement, enabled UM to evolve from a predominantly basic science research institution to one with a comprehensive research portfolio. This has been achieved on the foundation of: integrated and innovative training and educational programs that have touched nearly 2,000 trainees, faculty and staff;centralization and optimization of previously fragmented research services to create innovative opportunities for users;$10.2M distributed for pilot studies to accelerate innovation;and researcher participation in new partnerships with our communities and across the CTSA National Consortium. In the renewal period, CTSA funding leveraged with robust institutional support will enable MICHR to pursue 5 Overarching Objectives: 1) Optimize training and mentoring to create the next generation of research teams and clinical and translational investigators;2) Augment infrastructure and refine research services to reduce barriers and maximize research productivity across the entire translational research continuum;3) Foster collaborations and leverage innovative approaches and technologies to catalyze discovery;4) Enhance community- and practice-based partnerships to assure bi-directional learning, research, and implementation of findings to benefit health;5) Actively lead and contribute to national CTSA Consortium activities and engage in cross-CTSA collaborations. These will be achieved by: expanding education into new areas to strengthen the pipeline of CTR investigators and deploying more flexible training tools;strer^gthening existing services and launching new ones to impact study start-up times and recruitment;employing major informatics investments to fully integrate the needs of CTR investigators into IT landscape;utilizing new practice-based research networl

Public Health Relevance

Translating scientific discoveries into real health gains is challenging. In recent decades this translation has been tal

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
5TL1TR000435-07
Application #
8499468
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Sawczuk, Andrea
Project Start
2012-06-01
Project End
2017-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
7
Fiscal Year
2013
Total Cost
$467,064
Indirect Cost
$23,931
Name
University of Michigan Ann Arbor
Department
Pediatrics
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Tso, Ivy F; Taylor, Stephan F; Grove, Tyler B et al. (2017) Factor analysis of the Scale of Prodromal Symptoms: data from the Early Detection and Intervention for the Prevention of Psychosis Program. Early Interv Psychiatry 11:14-22
Valikodath, Nita G; Newman-Casey, Paula Anne; Lee, Paul P et al. (2017) Agreement of Ocular Symptom Reporting Between Patient-Reported Outcomes and Medical Records. JAMA Ophthalmol 135:225-231
Camaj, Anton; Zahuranec, Darin B; Paone, Gaetano et al. (2017) Organizational Contributors to the Variation in Red Blood Cell Transfusion Practices in Cardiac Surgery: Survey Results From the State of Michigan. Anesth Analg 125:975-980
Virani, Shama; Light, Emily; Peterson, Lisa A et al. (2016) Stability of methylation markers in head and neck squamous cell carcinoma. Head Neck 38 Suppl 1:E1325-31
Salata, Brian M; Hutton, David W; Levine, Deborah A et al. (2016) Cost-Effectiveness of Dabigatran (150 mg Twice Daily) and Warfarin in Patients ? 65 Years With Nonvalvular Atrial Fibrillation. Am J Cardiol 117:54-60
Akkina, Sarah R; Novis, Sarah J; Keshavarzi, Nahid R et al. (2016) Academic institution pilot study shows far fewer diagnoses of sinusitis than reported nationally. Laryngoscope Investig Otolaryngol 1:124-129
Carter, Julia D; Assari, Shervin (2016) Sustained Obesity and Depressive Symptoms over 6 Years: Race by Gender Differences in the Health and Retirement Study. Front Aging Neurosci 8:312
Pynnonen, Melissa A; Lynn, Shana; Kern, Hayley E et al. (2015) Diagnosis and treatment of acute sinusitis in the primary care setting: A retrospective cohort. Laryngoscope 125:2266-72
Tso, Ivy F; Fang, Yu; Phan, K Luan et al. (2015) Abnormal GABAergic function and face processing in schizophrenia: A pharmacologic-fMRI study. Schizophr Res 168:338-44
Tso, Ivy F; Calwas, Anita M; Chun, Jinsoo et al. (2015) Altered attentional and perceptual processes as indexed by N170 during gaze perception in schizophrenia: Relationship with perceived threat and paranoid delusions. J Abnorm Psychol 124:519-31

Showing the most recent 10 out of 20 publications