Cryptosporidium Enzymes as Chemotherapeutic Targets

Petersen, Carolyn

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project--Cooperative Agreements (U01)
• Project #: 5U01AI035123-03
• Application #: 2070545
• Study Section: Special Emphasis Panel (SRC (85))
• Project Start: 1994-01-01
• Project End: 1996-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of California San Francisco
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Doyle, P S; Kanaani, J; Wang, C C (1998) Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum. Exp Parasitol 89:9-15

Barnes, D A; Bonnin, A; Huang, J X et al. (1998) A novel multi-domain mucin-like glycoprotein of Cryptosporidium parvum mediates invasion. Mol Biochem Parasitol 96:93-110

Vasquez, J R; Gooze, L; Kim, K et al. (1996) Potential antifolate resistance determinants and genotypic variation in the bifunctional dihydrofolate reductase-thymidylate synthase gene from human and bovine isolates of Cryptosporidium parvum. Mol Biochem Parasitol 79:153-65

Gut, J; Nelson, R G (1994) Cryptosporidium parvum sporozoites deposit trails of 11A5 antigen during gliding locomotion and shed 11A5 antigen during invasion of MDCK cells in vitro. J Eukaryot Microbiol 41:42S-43S