Improvingthe efficiencyof surveillancefor healthcare-associatedinfections,antimicrobialresistance,and otheradverse eventsbyoptimizingavailableelectronichealthinformationsystemsprovidesthecapacityfor facilitiestofocus lesson datacollectionandmore on improvingprocessesand outcomes.This may be _articuladytrue in smallcommunityhospitalswhere staffingandotherresourcesare limited. Enhanced .=lectronicsurveillancealone,however,is notsufficientto accomplishthesepreventiongoals. Acquisition andapplicationof performanceimprovementskillsandtoolsvia multidisciplinareyducationalmodesare alsorequired. Leveragingthe increasedcapacityof combiningelectronicsurveillancewith collaborativeneh,:orkingto implementenhancementsis thefocusof the OhioState HealthNetworkInfectionControlCollaborative(OSHNICC). The OSHNICC is builtonthe foundationof the OhioState UniversityHealthSystem (OSUHS) ('the supportfacilities'),withits highlyintegratedelectronichealthinformationsystem,combinedwith the existingOhioState HealthNetwork(OHSN). OHSN hasfor >10 yearselectronicallyandoperationallylinkedOSUHS with severaloutlyingreferral communitiesof varyingsizes(=theoutreachfacilities').The existingOSU InformationWarehouse(IW), a richrepositoryof healthinformation,willbeoptimizedfor surveillancebysystematicretrospectiveidentificationof reliablesurrogatemarkersfor targetedevents,retrospedivecomparisonof electronicwithtraditionalsurveillancefor accuracy,and proposectivevalidationof surveillancemethodolgyfor accuracyand costefficiency. The existingelectronicinterfacebehveenOSUHS andoutreachfacilitieswillbe usedto expandelectronicsurveillancecapabilitytothesefacilities. Concurrently,organized multifacetedcollaborationto improveinfectioncontrolprocessinOSHNICC faciltieswill be conductedwithstandardizedlongitudinaml onitoringof processand outcomemeasuresas the metric for success. Enhancedelectronicsurveillancefor targeted pathogenswithantimicrobial resistancewill be institutedacrossthe entirenetworkwithrapidepidemiologicand molecularcharacterizationof transmission.Collaborativeinterventionsto improvebothprocessandoutcomeswillbetested_,;Athinthisne_h'_' orkusinga grouprandomizationstudydesign.The economicimpactof all phasesofthe init_tiath/ewill be estimated.P.-_OPJ2.A.NCE SFFE(S) (o_an_-.atJonc.ity, state)The Ohio State Unk,ersity, Columbus,OHBamesville Hospital,Bamesville,OHBamesville Health Care Center, Barnesville,OHMonroe CountyCare Center, Bamesville,OHMadison County Hospital,London,OHArbors at London,London,OHWoodsfieldNursingand RehabilitationCenter,Woodsfield,OHWyandotMemorial Hospital,Upper Sandusky,OH FairhavenCommunity,UpperSandusky,OHWyandot Manor, Upper Sandusky, OHMary Rutan Hospital, Bellefontaine, OHLoganAcres, Bellefontaine, OHBucyrusCommunityHospital,Bucyrus,OHAltercare of Bucyrus,Bucyrus,OHHeartlandof Bucyrus,Bucyrus,OHPHS 3_S(R_#. C'_.'34) Page 2_ Form Page 2 P,_.,.._.a!I,,'_est_jat:dProgramDirector(Last, First, Middle): Stevenson, Kurt BrownKEY PERSO._._-EL See..i:_='m_,c,-ts.Use conb'nuaEonpages as needed to provide the requiredinformation in the format shown below.S_a_v,'_hPL. '-P_..alI,,'w?s'_atcr.Us'.a,q _er key personnelin alphabeticalorder,lastname firsLt_a.,'_e eRA Commons User Name Organization Roleon ProjectStevenson, Kurt Brown INF_55CNTRL Ohio State University Principal InvestigatorCaswe11R, obert J. Ohio State University Co-InvestigatorJarjoura, David Ohio State University Co-lnvestigatorKamal, Jyoti Ohio State University Co-InvestigatorLemeshow, Stanley Ohio State University Co-InvestigatorMangino, Julie Ohio State University Co-InvestigatorMurray, David Ohio State University Co-InvestigatorPancholi, Preeti Ohio State University Co-InvestigatorWang, Shu-Hua Ohio State University Co-InvestigatorOTHER SIG,_'_FICANTCONTRIBUTORSt'&me Organization Role on ProjectBrady, Michael Columbus Children's Hospital Technical advisor-ResistanceSaltz, Joel H. Ohio State University Technical advisor- InforrnaticsHuman Embryonic Stem Ceils [] No [] YestfL%eproposedprojectInvolveshumanembryonicstem cells, list below the registrationumberof thespecificcell line(s)from the followinglist:h.'tD:llstemce!Is.n_h.aovlreaistry_nde .asD. Use conEnuationpages as needed.Ifa s:>e'_..,I:LneC=L'z'l,:cetre.'_-enc_dat_ _Emei.ncludea statementhatonefromtheRegistrywill beused.C,e_lUneDisclosure Pen'nission Statement. App_cabTeto SBIR/STTR Only. See SBIPJSTTRinstructions. [] Yes [] NoPHS 3_3 (Re-,,.09..'34) Page3-- Form Page 2-continuedNumbetrhefoflowingpagesconsecuth'etfhyroughouttheapplicaSonD.onotusesufSxesuchas4a,4b. P_-.,._,a_I:w-est_gator/ProgramDirector(Last. First, Middle): Stevenson, Kurt BrownThe f t,hepr_'_cipailnvest}gatorlprogramdirector must be provided at the top of each pdnted page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page NumbersFace Page.................................................................................................................................................. 1Description,

National Institute of Health (NIH)
National Center for Infectious Diseases (CID)
Research Project--Cooperative Agreements (U01)
Project #
Application #
Study Section
Special Emphasis Panel (ZCI1-TYM (10))
Program Officer
Llata, Eloisa
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Ohio State University
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Lin, Michael Y; Woeltje, Keith F; Khan, Yosef M et al. (2014) Multicenter evaluation of computer automated versus traditional surveillance of hospital-acquired bloodstream infections. Infect Control Hosp Epidemiol 35:1483-90
Wang, Shu-Hua; Khan, Yosef; Hines, Lisa et al. (2012) Methicillin-resistant Staphylococcus aureus sequence type 239-III, Ohio, USA, 2007-2009. Emerg Infect Dis 18:1557-65
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Dubberke, Erik R; Butler, Anne M; Yokoe, Deborah S et al. (2010) Multicenter study of surveillance for hospital-onset Clostridium difficile infection by the use of ICD-9-CM diagnosis codes. Infect Control Hosp Epidemiol 31:262-8
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