This proposal responds to RFA-DK-12-017, which requests applications for Research Sites to collaborate with existing Research Sites in the Lower Urinary Tract Dysfunction Research Network (LURN). In this application, the University of Washington (UW) seeks support for a Research Site to participate in efforts to unravel the clinically confounding symptoms of the lower urinary tract. This proposal was developed following the guidelines stipulated by the National Institute of Diabetes, Digestive and Kidney diseases (NIDDK).
The aim of the proposed UW Research Site, in conjunction with the Data Coordination Center and existing LURN Research Sites, is to expand on validating symptom-based instruments to measure early, late, transient, and persistent symptoms both in males and females, and to better define the phenotypes of men and women with symptoms of lower urinary tract dysfunction. The key responsibilities of the Research Site will be to adopt the study protocols developed by the LURN investigators, validate the developed Patient Reported Outcome (PRO) measures, recruit study participants, and conduct extensive characterization (phenotyping) of them.

Public Health Relevance

The aim of the proposed UW Research Site, in conjunction with the Data Coordination Center and existing LURN Research Sites, is to validate symptom-based instruments to measure early, late, transient, and persistent urinary symptoms both in males and females, and to better define the phenotypes of men and women with symptoms of lower urinary tract dysfunction. The relevance of the project Is to identify subgroups of persons with urinary symptoms, in order to find the causes of the symptoms and identify better treatment regimens.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01DK100011-01
Application #
8587430
Study Section
Special Emphasis Panel (ZDK1-GRB-G (M5))
Program Officer
Kirkali, Ziya
Project Start
2013-07-15
Project End
2018-05-31
Budget Start
2013-07-15
Budget End
2014-05-31
Support Year
1
Fiscal Year
2013
Total Cost
$369,489
Indirect Cost
$123,988
Name
University of Washington
Department
Urology
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195