Abstract

This project provides support for the participation of the Radiation Oncology Division of the University of Puerto Rico in the Radiation Therapy Oncology Group. This organization is constituted by a national group of academic institutions involved in prospective clinical research in radiation therapy of cancer. The University of Puerto Rico began its participation in the Radiation Therapy Oncology Group early in 1972. Study cases are contributed by the University Hospital, the San Juan City Hospital, and the Radiotherapy Institute of the Metropolitan Hospital, all of which form part of the academic radiation therapy program. An additional institution, the San Juan Oncologic Hospital, may begin accessing cases during F.Y. 1981. The program contributes: case registration in RTOG registries, case accession for groupwide protocols, pilot Phase II study cases, protocol development, committee participation, and scientific publications. Funds from this grant will be used for professional, technical, and clerical staff and for patient related expenses (lodging, laboratory and X-ray tests, travel, etc.).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA012258-15
Application #
3556109
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1979-03-01
Project End
1989-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
15
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of Puerto Rico Med Sciences
Department
Type
Schools of Medicine
DUNS #
City
San Juan
State
PR
Country
United States
Zip Code
00936

  Publications

Fu, K K; Clery, M; Ang, K K et al. (1995) Randomized phase I/II trial of two variants of accelerated fractionated radiotherapy regimens for advanced head and neck cancer: results of RTOG 88-09. Int J Radiat Oncol Biol Phys 32:589-97
Fu, K K; Pajak, T F; Marcial, V A et al. (1995) Late effects of hyperfractionated radiotherapy for advanced head and neck cancer: long-term follow-up results of RTOG 83-13. Int J Radiat Oncol Biol Phys 32:577-88
Fu, K K; Hammond, E; Pajak, T F et al. (1994) Flow cytometric quantification of the proliferation-associated nuclear antigen p105 and DNA content in advanced head & neck cancers: results of RTOG 91-08. Int J Radiat Oncol Biol Phys 29:661-71
Marcial, V A; Pajak, T F; Rotman, M et al. (1993) ""Compensated"" split-course versus continuous radiation therapy of carcinoma of the tonsillar fossa. Final results of a prospective randomized clinical trial of the Radiation Therapy Oncology Group. Am J Clin Oncol 16:389-96
Cox, J D; Pajak, T F; Marcial, V A et al. (1992) Interruptions adversely affect local control and survival with hyperfractionated radiation therapy of carcinomas of the upper respiratory and digestive tracts. New evidence for accelerated proliferation from Radiation Therapy Oncology Group Protocol 8313. Cancer 69:2744-8
Tupchong, L; Scott, C B; Blitzer, P H et al. (1991) Randomized study of preoperative versus postoperative radiation therapy in advanced head and neck carcinoma: long-term follow-up of RTOG study 73-03. Int J Radiat Oncol Biol Phys 20:21-8
Cox, J D; Pajak, T F; Marcial, V A et al. (1991) ASTRO plenary: interfraction interval is a major determinant of late effects, with hyperfractionated radiation therapy of carcinomas of upper respiratory and digestive tracts: results from Radiation Therapy Oncology Group protocol 8313. Int J Radiat Oncol Biol Phys 20:1191-5
Cox, J D; Pajak, T F; Marcial, V A et al. (1990) Dose-response for local control with hyperfractionated radiation therapy in advanced carcinomas of the upper aerodigestive tracts: preliminary report of radiation therapy oncology group protocol 83-13. Int J Radiat Oncol Biol Phys 18:515-21
Wallner, P E; Lustig, R A; Pajak, T F et al. (1989) Impact of initial quality control review on study outcome in lung and head/neck cancer studies--review of the Radiation Therapy Oncology Group experience. Int J Radiat Oncol Biol Phys 17:893-900
Marcial, V A; Pajak, T F; Kramer, S et al. (1988) Radiation Therapy Oncology Group (RTOG) studies in head and neck cancer. Semin Oncol 15:39-60

Showing the most recent 10 out of 15 publications