The Duluth CCOP, established and funded by the National Cancer Institute (NCI) in 1984, with successful competitive grant renewal in 1987, 1990, 1995, 2000, and 2005 is the only program of its kind in northern Minnesota and northwest Wisconsin and it is one of two CCOPs in Minnesota. The Duluth CCOP is comprised of physicians and ancillary support staff who practice under the umbrella of the St. Mary's Duluth Clinic Health System (SMDC) in three institutions in Duluth, MN: the St. Mary's Duluth Clinic Cancer Center (SMDCCC) St. Mary's Medical Center (SMMC) and SMDC Medical Center (formerly known as Miller Dwan Medical Center). Hematology/Oncology clinics are also served by SMDCCC hematologists/oncologists at various regional outreach sites throughout the SMDC catchment/service area. Geographically, the Duluth CCOP covers a large area including urban and rural areas, with a radius of over 150 miles from Duluth. The Duluth CCOP brings the benefits of clinical research to patients in a region that would be without access to clinical trials due to the distance from the nearest comprehensive cancer center. The strategy of the Duluth CCOP is to provide patients in the region access to state-of-the-art cancer care through participation in NCI supported treatment and cancer control protocols. The North Central Cancer Treatment Group will continue to function as the primary research base of the CCOP and secondary research bases will be the Eastern Cooperative Oncology Group, and the National Surgical Breast and Bowel Project. The Duluth CCOP will also continue to open trials through the Clinical Trial Support Unit of the NCI. Children have access to Children's Oncology Group studies via an affiliation between SMDCCC pediatric hematologists/oncologists and the University of Minnesota Masonic Cancer Center. The goal of the Duluth CCOP is to accrue annually 150 patient credits to treatment protocols and 220 patient credits to prevention/cancer control protocols. A robust culture of cancer care that supports multi-disciplinary treatments allows us to deliver the best possible therapy while maintaining a high level of accrual to clinical trials.
Enormous advances in cancer care have occurred as a result of increased understanding of cancer biology and in turn, the use of clinical trials to translate that knowledge to improved patient care and outcomes. The Duluth CCOP is a highly successful program that since 1984 has delivered state-of-the-art NCI clinical trials and cancer care to northern Minnesota and northwest Wisconsin.
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|Dy, Grace K; Molina, Julian R; Qi, Yingwei et al. (2014) NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status. J Thorac Oncol 9:1146-53|
|Loprinzi, Charles L; Qin, Rui; Dakhil, Shaker R et al. (2014) Phase III randomized, placebo-controlled, double-blind study of intravenous calcium and magnesium to prevent oxaliplatin-induced sensory neurotoxicity (N08CB/Alliance). J Clin Oncol 32:997-1005|
|Province, M A; Goetz, M P; Brauch, H et al. (2014) CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations. Clin Pharmacol Ther 95:216-27|
|Dronca, Roxana S; Allred, Jacob B; Perez, Domingo G et al. (2014) Phase II study of temozolomide (TMZ) and everolimus (RAD001) therapy for metastatic melanoma: a North Central Cancer Treatment Group study, N0675. Am J Clin Oncol 37:369-76|
|Galanis, Evanthia; Anderson, S Keith; Lafky, Jackie M et al. (2013) Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial. Clin Cancer Res 19:4816-23|
|Atherton, Pamela J; Halyard, Michele Y; Sloan, Jeff A et al. (2013) Assessment of patient-reported measures of bowel function before and after pelvic radiotherapy: an ancillary study of the North Central Cancer Treatment Group study N00CA. Support Care Cancer 21:1193-9|
|Barton, Debra L; Burger, Kelli; Novotny, Paul J et al. (2013) The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9. Support Care Cancer 21:1185-92|
|Barton, Debra L; Liu, Heshan; Dakhil, Shaker R et al. (2013) Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2. J Natl Cancer Inst 105:1230-8|
|Kottschade, Lisa A; Suman, Vera J; Perez, Domingo G et al. (2013) A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma : a North Central Cancer Treatment Group study, N0775. Cancer 119:586-92|
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