Since 2000, the Southern Consortium Node (SCN) has worked closely with community partners and colleagues nationwide in research and dissemination activities designed to improve the treatment of addictions through research and implementation of evidence-based practice. In this renewal application, the SCN proposes to expand to include a broader region of the southeast through partnership with Duke University, a national leader in medical research. Duke University is an ideal partner because of their complementary scientific expertise, strong primary care and HIV research activities, geographic proximity and prior experience with CTN activities. The partnership will extend the SCN's regional and geographic distribution to span a large portion of the Southeastern US and bring close connections with well-established primary care and HIV clinical research networks to broaden the types of clinical settings and patient populations available for CTN trials. The SCN will establish a robust collaboration with the CTSA initiative through a number of individuals who will serve as investigators on both the CTN and CTSA, including Dr. Brady who is the PI of the MUSC CTSA. The primary specific aims for the next five years are: to extend the geographic reach of the SCN to include CTPs and academic partners in South Carolina, North Carolina, Georgia, Tennessee and Mississippi. To develop research sites in primary care and medical specialty clinics that will expand the diversity of and number of participants available to participate in CTN trials. To increase the use of CTN as a training platform and a research platform for non-CTN research. To develop a robust collaboration between the CTN and both local and national CTSAs for the purpose of bidirectional sharing of "best-practices", informatics and trial design strategies across networks. To expand the scientific expertise available to the CTN through partnership of investigators at MUSC and Duke University.

Public Health Relevance

The CTN is a cooperative agreement between NIDA, treatment providers and researchers throughout the nation in which science is being utilized as a vehicle to improve the treatment of addictions. It is the goal of the SCN to work collaboratively with NIDA, the newly established coordinating a data centers, and other CTN Nodes in conducting and directing multi-site clinical trials and dissemination efforts.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10DA013727-13S1
Application #
8606592
Study Section
Special Emphasis Panel (ZDA1-KXH-C (04))
Program Officer
Dobbins, Ronald
Project Start
2000-09-30
Project End
2015-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
13
Fiscal Year
2013
Total Cost
$882,991
Indirect Cost
$83,322
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
McClure, Erin A; Baker, Nathaniel L; Gipson, Cassandra D et al. (2015) An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers. Am J Drug Alcohol Abuse 41:52-6
Meade, Christina S; Bevilacqua, Lisa A; Moore, Elizabeth D et al. (2014) Concurrent substance abuse is associated with sexual risk behavior among adults seeking treatment for prescription opioid dependence. Am J Addict 23:27-33
McClure, Erin A; Acquavita, Shauna P; Dunn, Kelly E et al. (2014) Characterizing smoking, cessation services, and quit interest across outpatient substance abuse treatment modalities. J Subst Abuse Treat 46:194-201
Campbell, Aimee N C; Nunes, Edward V; Matthews, Abigail G et al. (2014) Internet-delivered treatment for substance abuse: a multisite randomized controlled trial. Am J Psychiatry 171:683-90
Mannelli, Paolo; Wu, Li-Tzy; Peindl, Kathleen S et al. (2014) Extended release naltrexone injection is performed in the majority of opioid dependent patients receiving outpatient induction: a very low dose naltrexone and buprenorphine open label trial. Drug Alcohol Depend 138:83-8
McCauley, Jenna L; Mercer, Mary Ashley; Barth, Kelly S et al. (2014) Pain management perceptions among prescription opioid dependent individuals. Drug Alcohol Depend 142:354-8
Crits-Christoph, Paul; Gallop, Robert; Sadicario, Jaclyn S et al. (2014) Predictors and moderators of outcomes of HIV/STD sex risk reduction interventions in substance abuse treatment programs: a pooled analysis of two randomized controlled trials. Subst Abuse Treat Prev Policy 9:3
Merghati-Khoei, Effat; Sheikhan, Fatemeh; Shamsalizadeh, Neda et al. (2014) Menopause negatively impacts sexual lives of middle-aged Iranian women: a cross-sectional study. J Sex Marital Ther 40:552-60
Wells, Elizabeth A; Donovan, Dennis M; Daley, Dennis C et al. (2014) Is level of exposure to a 12-step facilitation therapy associated with treatment outcome? J Subst Abuse Treat 47:265-74
Winhusen, Theresa M; Kropp, Frankie; Theobald, Jeff et al. (2014) Achieving smoking abstinence is associated with decreased cocaine use in cocaine-dependent patients receiving smoking-cessation treatment. Drug Alcohol Depend 134:391-5

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