Infection with C. trachomatis has decreased substantially in trachoma endemic areas following repeated annual mass drug administration with azithromycin, although not as rapidly as anticipated. We propose to conduct a clinical trial to determine the added benefit for communities, which are now at low levels of infection, of a program to identify and treat new families who came after mass treatment, and travelers who return to the community, as they could be the source of re-emergent infection. The proportion of communities who are able to stop mass treatment will be compared in the group of communities randomized to mass treatment plus the newcomer treatment program compared to the communities randomized to mass treatment alone.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
1U10EY022584-01
Application #
8337987
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Program Officer
Everett, Donald F
Project Start
2012-09-01
Project End
2016-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
1
Fiscal Year
2012
Total Cost
$978,043
Indirect Cost
$301,865
Name
Johns Hopkins University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218