The Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (MFMU) Network was created in 1986 to conduct clinical research studies in obstetrics and perinatal medicine. The Network consists of a number of major academic clinical centers, a data coordinating center, and the Institute itself. The research) studies, principally randomized trials but also observational studies, are aimed at reducing maternal, fetal and infant morbidity related to preterm birth, fetal growth abnormalities and maternal complications and to provide the rationale for evidence-based, cost- effective, obstetric practice. The data coordinating center is a criticaly important part of this collaborative effort. The overall purpose of the coordinating center is to mal

Public Health Relevance

of the proposed research to public health is clear and direct. The results of the MFMU Network's studies can benefit potentially pregnant women and their children worldwide, by finding methods to screen for problems in pregnancy, treatments that for pregnant women that improve their and their children's health, and especially finding treatments that can help lessen the problem of babies being born too early.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10HD036801-16
Application #
8528874
Study Section
Special Emphasis Panel (ZHD1-DSR-Z (54))
Program Officer
Ilekis, John V
Project Start
1998-04-15
Project End
2018-11-30
Budget Start
2014-01-01
Budget End
2014-11-30
Support Year
16
Fiscal Year
2014
Total Cost
$12,128,227
Indirect Cost
$863,205
Name
George Washington University
Department
Biostatistics & Other Math Sci
Type
Schools of Public Health
DUNS #
043990498
City
Washington
State
DC
Country
United States
Zip Code
20052
Varner, Michael W; Rice, Madeline Murguia; Landon, Mark B et al. (2017) Pregnancies After the Diagnosis of Mild Gestational Diabetes Mellitus and Risk of Cardiometabolic Disorders. Obstet Gynecol 129:273-280
Tita, Alan T N; Lai, Yinglei; Landon, Mark B et al. (2017) Predictive Characteristics of Elevated 1-Hour Glucose Challenge Test Results for Gestational Diabetes. Am J Perinatol 34:1464-1469
Chauhan, Suneet P; Rice, Madeline Murguia; Grobman, William A et al. (2017) Neonatal Morbidity of Small- and Large-for-Gestational-Age Neonates Born at Term in Uncomplicated Pregnancies. Obstet Gynecol 130:511-519
Casey, Brian M; Thom, Elizabeth A; Peaceman, Alan M et al. (2017) Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy. N Engl J Med 376:815-825
Sutton, Elizabeth F; Cain, Loren E; Vallo, Porsha M et al. (2017) Strategies for Successful Recruitment of Pregnant Patients Into Clinical Trials. Obstet Gynecol 129:554-559
Silver, Robert M; Myatt, Leslie; Hauth, John C et al. (2017) Cell-Free Total and Fetal DNA in First Trimester Maternal Serum and Subsequent Development of Preeclampsia. Am J Perinatol 34:191-198
Harper, Lorie M; Mele, Lisa; Landon, Mark B et al. (2016) Carpenter-Coustan Compared With National Diabetes Data Group Criteria for Diagnosing Gestational Diabetes. Obstet Gynecol 127:893-8
Cheong-See, Fiona; Schuit, Ewoud; Arroyo-Manzano, David et al. (2016) Prospective risk of stillbirth and neonatal complications in twin pregnancies: systematic review and meta-analysis. BMJ 354:i4353
McDonnold, Mollie; Mele, Lisa M; Myatt, Leslie et al. (2016) Waist-to-Hip Ratio versus Body Mass Index as Predictor of Obesity-Related Pregnancy Outcomes. Am J Perinatol 33:618-24
Thom, Elizabeth A; Rice, Madeline Murguia; Saade, George R et al. (2016) What we have learned about the design of randomized trials in pregnancy. Semin Perinatol 40:328-34

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