The Autoimmunity Centers of Excellence Discretionary Fund supports Pilot Research Projects, Clinical Trials, and Mechanistic Research and Shared Research Agenda Projects for a variety of autoimmune diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI056363-10
Application #
8466193
Study Section
Special Emphasis Panel (ZAI1-QV-I)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
10
Fiscal Year
2013
Total Cost
$6,351,285
Indirect Cost
$1,681,632
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Look, Michael; Saltzman, W Mark; Craft, Joe et al. (2014) The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus. Biomaterials 35:1089-95
Spencer, Diane M; Gauley, Julie; Pisetsky, David S (2014) The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis. Innate Immun 20:239-48
Pop, Laurentiu M; Barman, Stephen; Shao, Chunli et al. (2014) A reevaluation of CD22 expression in human lung cancer. Cancer Res 74:263-71
Ullal, Anirudh J; Marion, Tony N; Pisetsky, David S (2014) The role of antigen specificity in the binding of murine monoclonal anti-DNA antibodies to microparticles from apoptotic cells. Clin Immunol 154:178-87
Candando, Kathleen M; Lykken, Jacquelyn M; Tedder, Thomas F (2014) B10 cell regulation of health and disease. Immunol Rev 259:259-72
Lykken, Jacquelyn M; DiLillo, David J; Weimer, Eric T et al. (2014) Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice. J Immunol 193:746-56
Poe, Jonathan C; Kountikov, Evgueni I; Lykken, Jacquelyn M et al. (2014) EndoU is a novel regulator of AICD during peripheral B cell selection. J Exp Med 211:57-69
Luo, Wei; Mayeux, Jessica; Gutierrez, Toni et al. (2014) A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. J Immunol 193:909-20
Hershberg, Uri; Meng, Wenzhao; Zhang, Bochao et al. (2014) Persistence and selection of an expanded B-cell clone in the setting of rituximab therapy for Sjögren's syndrome. Arthritis Res Ther 16:R51
Wang, Xiao; Stearns, Nancy A; Li, Xingfu et al. (2014) The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects. Clin Immunol 153:94-103

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