The goals of the Administrative Core are to provide administrative support and structure for the multi-project grant program projects. Specifically, the Administrative Core will 1) provide administrative oversight for the scientific conduct of each of the projects, ensuring that overlap does not occur in the individual projects;2) provide administrative oversight related to the budgetary interactions between the University of Pittsburgh, Rutgers University and Millenia Hope Inc.;3) interact with NIH program staff relating to the goals of this U19 multi-project cooperative grant program for the preclinical development of ribonuclease H inhibitors;4) plan, schedule and coordinate the annual meeting of the Scientific Steering Committee comprised of key personnel from the program project grant, Scientific Advisory Panel members, and NIAID/NIMH Scientific Coordinators;and 5) plan, schedule and conduct monthly teleconferences among the Project Leaders and key personnel.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI073975-05
Application #
8218097
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
2012-08-31
Budget Start
2011-03-01
Budget End
2012-08-31
Support Year
5
Fiscal Year
2011
Total Cost
$65,236
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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Kirby, Karen A; Marchand, Bruno; Ong, Yee Tsuey et al. (2012) Structural and inhibition studies of the RNase H function of xenotropic murine leukemia virus-related virus reverse transcriptase. Antimicrob Agents Chemother 56:2048-61
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Sarafianos, Stefan G; Marchand, Bruno; Das, Kalyan et al. (2009) Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. J Mol Biol 385:693-713