As described in the Overview section of this proposal (Overview. D. 3. Organization Administration and Oversight) this core provides support for Dr. Braciale as Program Director. He will coordinate all of the research efforts and establish the priorities of the group. He will ensure that the timetables/milestones outlined in the program are met. He will be the primary interface with the programmatic representative from NIAID. His offices and laboratories are located in the Carter Immunology Center, University of Virginia. The To Be Determined Program Manager will be responsible for coordinating and management of the fiscal activities of the Projects and Cores. This individual will also be responsible for organizing and managing of meetings of the researchers, their travel, the management of data transmitted among researchers, and will assist the Program Director in establishing that the time tables and milestones outlined in the program are met. This individual will be housed in the Carter Immunology Center in space adjoining the Program Director. Ms. Cindy Li is the fiscal technician for the Carter Immunology Center. She will be responsible for fiscal account reconciliation for all the Projects and Cores and will oversee along with the Program Manager the receipt and reconciliation of data on expenditures in Project 4 carried out at Dartmouth.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI083024-04
Application #
8375788
Study Section
Special Emphasis Panel (ZAI1-BDP-I)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
4
Fiscal Year
2012
Total Cost
$82,000
Indirect Cost
$29,376
Name
University of Virginia
Department
Type
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Teoh, Jeffrey J; Gamache, Awndre E; Gillespie, Alyssa L et al. (2016) Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation. J Immunol 197:4360-4370
Jiang, Li; Yao, Shuyu; Huang, Su et al. (2016) Type I IFN signaling facilitates the development of IL-10-producing effector CD8(+) T cells during murine influenza virus infection. Eur J Immunol 46:2778-2788
DeBerge, Matthew P; Ely, Kenneth H; Wright, Peter F et al. (2015) Shedding of TNF receptor 2 by effector CD8⁺ T cells by ADAM17 is important for regulating TNF-α availability during influenza infection. J Leukoc Biol 98:423-34
Kim, Taeg S; Hanak, Mark; Trampont, Paul C et al. (2015) Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells. J Clin Invest 125:3965-80
Krueger, Peter D; Kim, Taeg S; Sung, Sun-Sang J et al. (2015) Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ. J Immunol 194:3213-22
Ramana, Chilakamarti V; DeBerge, Matthew P; Kumar, Aseem et al. (2015) Inflammatory impact of IFN-γ in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways. Am J Physiol Lung Cell Mol Physiol 308:L650-7
Steinke, John W; Liu, Lixia; Turner, Ronald B et al. (2015) Immune surveillance by rhinovirus-specific circulating CD4+ and CD8+ T lymphocytes. PLoS One 10:e0115271
Moser, Emily K; Sun, Jie; Kim, Taeg S et al. (2015) IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after Influenza A virus infection. PLoS One 10:e0120169
Moser, Emily K; Hufford, Matthew M; Braciale, Thomas J (2014) Late engagement of CD86 after influenza virus clearance promotes recovery in a FoxP3+ regulatory T cell dependent manner. PLoS Pathog 10:e1004315
DeBerge, Matthew P; Ely, Kenneth H; Enelow, Richard I (2014) Soluble, but not transmembrane, TNF-α is required during influenza infection to limit the magnitude of immune responses and the extent of immunopathology. J Immunol 192:5839-51

Showing the most recent 10 out of 48 publications