The Data Management. Bioinformatics. and Biostatistics Core (DMBBC) will provide (1) the data management system, and (2) the personnel for storing, organizing and analyzing the different data types generated by the Center for the Study of Complex Malaria in India (CSCMi). The data management system - - a suite of databases and data management software tools built in collaboration with the Indian technology solutions company MGL ~ will be housed at the NIMR Dwarka campus in New Delhi but be accessible to the widespread US and Indian staff of the CSCMi via secure Intemet connections. DMBBC personnel will provide dedicated data management, biostatistics. and bioinformatics expertise to CSCMi researchers to help them complete their Center projects. They also will provide training to Indian scientists in the areas of experimental design and sampling, statistical analysis and bioinformafic analysis of data, dynamic programming, and scienfific manuscript wrifing. In these ways the DMBBC will make a crucial contribution to the CSCMi's objectives of developing the knowledge, tools and evidence-based strategies needed to support the intervention and control programs of Indian government organizations;building research capacity in India;and training the next generation of malaria and mosquito vector biologists.

Public Health Relevance

Malaria is a major public health problem in India, the world's largest democracy and second most populous country. This Core provides data infrastructure, data analysis tools and bioscience software expertise to support the Center for the Study of Complex Malaria in India, which is dedicated to enhancing the malaria intervention and control programs of Indian government organizations.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-AWA-M)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
New York University
New York
United States
Zip Code
Mohanty, Sanjib; Benjamin, Laura A; Majhi, Megharay et al. (2017) Magnetic Resonance Imaging of Cerebral Malaria Patients Reveals Distinct Pathogenetic Processes in Different Parts of the Brain. mSphere 2:
Waite, Jessica L; Swain, Sunita; Lynch, Penelope A et al. (2017) Increasing the potential for malaria elimination by targeting zoophilic vectors. Sci Rep 7:40551
Thomas, Shalu; Ravishankaran, Sangamithra; Justin, N A Johnson Amala et al. (2017) Resting and feeding preferences of Anopheles stephensi in an urban setting, perennial for malaria. Malar J 16:111
Wassmer, Samuel Crocodile; Grau, Georges Emile Raymond (2017) Severe malaria: what's new on the pathogenesis front? Int J Parasitol 47:145-152
Mooney, Jason Paul; Wassmer, Samuel Crocodile; Hafalla, Julius Clemence (2017) Type I Interferon in Malaria: A Balancing Act. Trends Parasitol 33:257-260
Beck-Johnson, Lindsay M; Nelson, William A; Paaijmans, Krijn P et al. (2017) The importance of temperature fluctuations in understanding mosquito population dynamics and malaria risk. R Soc Open Sci 4:160969
Uplekar, Swapna; Rao, Pavitra Nagesh; Ramanathapuram, Lalitha et al. (2017) Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays. PLoS Negl Trop Dis 11:e0005323
Gruszczyk, Jakub; Lim, Nicholas T Y; Arnott, Alicia et al. (2016) Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement. Proc Natl Acad Sci U S A 113:E191-200
Thomas, Shalu; Ravishankaran, Sangamithra; Justin, Johnson A et al. (2016) Overhead tank is the potential breeding habitat of Anopheles stephensi in an urban transmission setting of Chennai, India. Malar J 15:274
Gallego-Delgado, Julio; Basu-Roy, Upal; Ty, Maureen et al. (2016) Angiotensin receptors and ?-catenin regulate brain endothelial integrity in malaria. J Clin Invest 126:4016-4029

Showing the most recent 10 out of 57 publications