An Administrative Core will coordinate and facilitate all activities within the U19 Human Immune Profiling Research Group. This Core will be responsible for the overall organizafion, management, decision-making, and ufilization of institutional resources. The Administrative Core will provide oversight and consultation to each of the Research and Scientific Core Projects to ensure that scientific objectives are met and that there is opfimal ufilization of resources. Specifically, the Administrative Core will: monitor and assist each group so that their goals are achieved and emergent problems are expedifiously addressed;provide fiscal management and ensure cost-effective ufilizafion of U19 resources;promote the communication and disseminafion of research and technology;and organize the presentafion and publicafion of data. This Core will also ensure data sharing, protecfion of intellectual property, and long-term data storage in coordination with the Data Repository.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI089992-05
Application #
8699132
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Yale University
Department
Type
DUNS #
City
New Haven
State
CT
Country
United States
Zip Code
06510
Yao, Yi; Montgomery, Ruth R (2016) Role of Immune Aging in Susceptibility to West Nile Virus. Methods Mol Biol 1435:235-47
Montgomery, Ruth R (2016) High standards for high dimensional investigations. Cytometry A 89:886-888
Das, Rituparna; Loughran, Kerry; Murchison, Charles et al. (2016) Association between high expression macrophage migration inhibitory factor (MIF) alleles and West Nile virus encephalitis. Cytokine 78:51-4
Montgomery, Ruth R; Murray, Kristy O (2015) Risk factors for West Nile virus infection and disease in populations and individuals. Expert Rev Anti Infect Ther 13:317-25
Strauss-Albee, Dara M; Fukuyama, Julia; Liang, Emily C et al. (2015) Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility. Sci Transl Med 7:297ra115
Mohanty, Subhasis; Joshi, Samit R; Ueda, Ikuyo et al. (2015) Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis 211:1174-84
Qian, Feng; Goel, Gautam; Meng, Hailong et al. (2015) Systems immunology reveals markers of susceptibility to West Nile virus infection. Clin Vaccine Immunol 22:6-16
Qian, Feng; Montgomery, Ruth R (2015) Imaging Immunosenescence. Methods Mol Biol 1343:97-106
Thakar, Juilee; Mohanty, Subhasis; West, A Phillip et al. (2015) Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination. Aging (Albany NY) 7:38-52
Tsioris, Konstantinos; Gupta, Namita T; Ogunniyi, Adebola O et al. (2015) Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing. Integr Biol (Camb) 7:1587-97

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