This application proposes """"""""The National Dental PBRN (NDPBRN)"""""""", a national collaborative of practices and organizations across the United States that will engage practitioners in the excitement of discovery for the benefit of everyday clinical practice and its patients. Consistent with specifications in the RFA itself, the Specific Aims will be to: (1) support the infrastructure and conduct of national oral health research studies in dental practices on topics of importance to practitioners;(2) provide evidence useful in daily patient care;(3) facilitate the translation of research findings into clinical practice. NDPBRN also will aim to broaden the scope of dental practice via certain studies to better integrate dental practice into the larger health care system, and to reach out further to dental education to inculcate in graduating clinicians an appreciation for the role of science in everyday clinical practice. NDPBRN will measure and document this change and the network's impact on bringing about change in everyday clinical practice. NDPBRN will accomplish these aims by building upon the many lessons learned from its exceptionally productive current national network, and include additional states and activities. We are fortunate to have gained important experience these past six years using the same regional funding structure and administrative structure mandated in the RFA. The effectiveness of this structure is evident from our current network's high level of productivity, as judged by number of publications and completed studies, the size, scope, quality (e.g. Good Clinical Practice audit trail standards), and diversity of studies, and impact on health and daily clinical practice. NDPBRN will comprise six regions, a Data Coordinating Core (mainly at Westat, Inc.), and an Administrative Core largely based at the University of Alabama at Birmingham (UAB). Other key elements of the governing and administrative structure will include a Practitioner Steering Committee, Regional Directors Committee, Director of Dental Informatics, Director of Communications &Dissemination, Director of Practitioner Training &Education Component, Director of Academic Collaborations, Protocol Consultants Group, Patient Advisory Board, Publications &Presentations Committee, Central IRB, Data &Safety Monitoring Board, and NIDCR staff. The Western region will be led by Kaiser Permanente, the Midwest region by Health Partners Research Foundation, the Southwest region by the Univ. of Texas Health Science Center at San Antonio, the South Central region by UAB, the South Atlantic region by the Univ. of Florida, and the Northeast region by the Univ. of Rochester.

Public Health Relevance

The network's overall goal will be to do science that is immediately applicable to everyday clinical practice, to foster its movement into everyday clinical practice, and thereby help improve the health of the nation. NDPBRN will continue to comprise a highly collaborative environment wherein clinicians in everyday clinical practice, academic researchers, patient representatives, and their communities become engaged in win-win activities that each group sees as mutually beneficial.

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZDE1)
Program Officer
Denucci, D J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
Schools of Dentistry/Oral Hygn
United States
Zip Code
Nixdorf, Donald R; Law, Alan S; Lindquist, Kimberly et al. (2016) Frequency, impact, and predictors of persistent pain after root canal treatment: a national dental PBRN study. Pain 157:159-65
Eleazer, Paul D; Gilbert, Gregg H; Funkhouser, Ellen et al. (2016) Techniques and materials used by general dentists during endodontic treatment procedures: Findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 147:19-27
Funkhouser, Ellen; Vellala, Kavya; Baltuck, Camille et al. (2016) Survey Methods to Optimize Response Rate in the National Dental Practice-Based Research Network. Eval Health Prof :
Makhija, Sonia K; Lawson, Nathaniel C; Gilbert, Gregg H et al. (2016) Dentist material selection for single-unit crowns: Findings from the National Dental Practice-Based Research Network. J Dent 55:40-47
Pigg, Maria; Nixdorf, Donald R; Nguyen, Ruby H N et al. (2016) Validity of Preoperative Clinical Findings to Identify Dental Pulp Status: A National Dental Practice-Based Research Network Study. J Endod 42:935-42
Cutrona, Sarah L; Sadasivam, Rajani S; DeLaughter, Kathryn et al. (2016) Online tobacco websites and online communities-who uses them and do users quit smoking? The quit-primo and national dental practice-based research network Hi-Quit studies. Transl Behav Med 6:546-557
McCracken, Michael S; Louis, David R; Litaker, Mark S et al. (2016) Treatment recommendations for single-unit crowns: Findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 147:882-890
Yokoyama, Yoko; Kakudate, Naoki; Sumida, Futoshi et al. (2016) Evidence-practice gap for dental sealant application: results from a dental practice-based research network in Japan. Int Dent J 66:330-336
Mungia, Rahma; Buchberg, Meredith; Hayes, Holly et al. (2016) Connecting and Collaborating: Developing National Dental PBRN Study Concepts Through POD Engagement. Health Promot Pract 17:278-84
Nixdorf, Donald R; Law, Alan S; John, Mike T et al. (2015) Differential diagnoses for persistent pain after root canal treatment: a study in the National Dental Practice-based Research Network. J Endod 41:457-63

Showing the most recent 10 out of 58 publications