The Informatics Core is part of the Consortium for the """"""""Collaborative Initiative on Fetal Alcohol Spectrum Disorders"""""""" (CIFASD). The theme of this collaborative initiative is a cross-cultural assessment of """"""""fetal alcohol spectrum disorder"""""""" (FASD). The CIFASD will coordinate basic, behavioral, and clinical investigators in a multidisciplinary research project to better inform approaches aimed at developing effective intervention and treatment approaches for FASD. It will involve the input and contributions from basic researchers, behavioral scientists, and clinical investigators with the willingness to utilize novel and cutting-edge techniques so as not to simply replicate previous or ongoing work, but rather to try and move it forward in a rigorous fashion. The Informatics Core will develop and maintain the CIFASD Data Repository, which will be used to collect, maintain and distribute data generated by the various participants in the consortium. The Informatics Core will be responsible for working with the other consortium participants to define a Data Dictionary to be used in standardizing data collection, enabling the transfer of data to and from the CIFASD Data Repository, consulting on how to establish local data management systems, providing both software tools and consulting to consortium participants, and producing status reports about the progress of the various projects within the consortium. The Informatics Core draws on a wealth of resources, experience, and expertise at Indiana University in information technology infrastructure and data management, The CIFASD Data Repository will be developed on Indiana University's state-of-the-art central supercomputing facilities, taking advantage of Indiana University's strong commitment to institutional computational resources. Resources that will be used to implement the CIFASD Data Repository include multiple supercomputers, an array of readily available database and statistical software, and a high- speed, secure, robust data archiving system capable of storing duplicate copies in multiple physical locations separated by more than fifty miles. The Informatics Core will use these extraordinary computational resources to provide a single, highly secure location for consortium participants to obtain the cross-cultural data that will enable the CIFASD to meet its goals of developing novel techniques for intervention and treatment of FASD.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24AA014818-08
Application #
8125029
Study Section
Special Emphasis Panel (ZAA1-CC (11))
Program Officer
Dunty, Jr, William
Project Start
2003-09-30
Project End
2012-07-31
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
8
Fiscal Year
2011
Total Cost
$193,413
Indirect Cost
Name
Indiana University Bloomington
Department
Miscellaneous
Type
Schools of Education
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47401
Wozniak, Jeffrey R; Mueller, Bryon A; Mattson, Sarah N et al. (2016) Functional connectivity abnormalities and associated cognitive deficits in fetal alcohol Spectrum disorders (FASD). Brain Imaging Behav :
Glass, Leila; Graham, Diana M; Deweese, Benjamin N et al. (2014) Correspondence of parent report and laboratory measures of inattention and hyperactivity in children with heavy prenatal alcohol exposure. Neurotoxicol Teratol 42:43-50
Ware, Ashley L; Glass, Leila; Crocker, Nicole et al. (2014) Effects of prenatal alcohol exposure and attention-deficit/hyperactivity disorder on adaptive functioning. Alcohol Clin Exp Res 38:1439-47
Nguyen, Tanya T; Glass, Leila; Coles, Claire D et al. (2014) The clinical utility and specificity of parent report of executive function among children with prenatal alcohol exposure. J Int Neuropsychol Soc 20:704-16
Ware, Ashley L; O'Brien, Jessica W; Crocker, Nicole et al. (2013) The effects of prenatal alcohol exposure and attention-deficit/hyperactivity disorder on psychopathology and behavior. Alcohol Clin Exp Res 37:507-16
Glass, Leila; Ware, Ashley L; Crocker, Nicole et al. (2013) Neuropsychological deficits associated with heavy prenatal alcohol exposure are not exacerbated by ADHD. Neuropsychology 27:713-24
Graham, Diana M; Crocker, Nicole; Deweese, Benjamin N et al. (2013) Prenatal alcohol exposure, attention-deficit/hyperactivity disorder, and sluggish cognitive tempo. Alcohol Clin Exp Res 37 Suppl 1:E338-46
Mattson, Sarah N; Roesch, Scott C; Glass, Leila et al. (2013) Further development of a neurobehavioral profile of fetal alcohol spectrum disorders. Alcohol Clin Exp Res 37:517-28
Ware, Ashley L; Crocker, Nicole; O'Brien, Jessica W et al. (2012) Executive function predicts adaptive behavior in children with histories of heavy prenatal alcohol exposure and attention-deficit/hyperactivity disorder. Alcohol Clin Exp Res 36:1431-41
Mattson, Sarah N; Foroud, Tatiana; Sowell, Elizabeth R et al. (2010) Collaborative initiative on fetal alcohol spectrum disorders: methodology of clinical projects. Alcohol 44:635-41

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