The Analytical Resources Core is composed of three subcores: 1) Hormone Assay and Analytical Services;2) Lipids and Lipoproteins;and 3) Mouse Pathology. These subcores share resources with others in the Vanderbilt DRTC where they have served to streamline research activities, produce cost-effective lines of experimentation, foster collaborative enterprises, and provide alternative outlets to scientists reaching the technical limits of their own laboratories. The services offered by each subcore are unique in their application to the mouse, and great effort has been made to establish assay specificity and scale down sample size to accommodate samples from this species. The Core provides space, equipment, and personnel for sample analyses and method development. Investigators pay a fee-for-service that covers the cost of reagents, supplies, a percentage of personnel salary, and pro-rated service contracts.
The Analytical Resources Core provides chemical analyses and pathology services for biological specimens obtained from genetic mouse models of diabetes and metabolic disease. The services provided by this Core are essential to understanding the specific genes that underlie these conditions.
|Gupta, Madhu; Solanki, Malvika H; Chatterjee, Prodyot K et al. (2014) Maternal magnesium deficiency in mice leads to maternal metabolic dysfunction and altered lipid metabolism with fetal growth restriction. Mol Med 20:332-40|
|Barnes, Tammy M; Otero, Yolanda F; Elliott, Amicia D et al. (2014) Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas. Am J Physiol Endocrinol Metab 307:E896-905|
|Kang, Li; Mayes, Wesley H; James, Freyja D et al. (2014) Matrix metalloproteinase 9 opposes diet-induced muscle insulin resistance in mice. Diabetologia 57:603-13|
|Patel, Manishkumar; Gleason, Alexa; O'Malley, Stacey et al. (2014) Non-invasive bioluminescence imaging of ?-cell function in obese-hyperglycemic [ob/ob] mice. PLoS One 9:e106693|
|Babaev, Vladimir R; Hebron, Katie E; Wiese, Carrie B et al. (2014) Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice. J Lipid Res 55:2296-308|
|Lee, Stacey; Page-McCaw, Patrick; Gamse, Joshua T (2014) Kctd12 and Ulk2 partner to regulate dendritogenesis and behavior in the habenular nuclei. PLoS One 9:e110280|
|Cordoba-Chacon, Jose; Gahete, Manuel D; McGuinness, Owen P et al. (2014) Differential impact of selective GH deficiency and endogenous GH excess on insulin-mediated actions in muscle and liver of male mice. Am J Physiol Endocrinol Metab 307:E928-34|
|Huang, Xuan; Hernandez, Ciria C; Hu, Ningning et al. (2014) Three epilepsy-associated GABRG2 missense mutations at the ?+/?- interface disrupt GABAA receptor assembly and trafficking by similar mechanisms but to different extents. Neurobiol Dis 68:167-79|
|Zhu, Lin; Martinez, Melissa N; Emfinger, Christopher H et al. (2014) Estrogen signaling prevents diet-induced hepatic insulin resistance in male mice with obesity. Am J Physiol Endocrinol Metab 306:E1188-97|
|Prins, Petra A; Hill, Michael F; Airey, David et al. (2014) Angiotensin-induced abdominal aortic aneurysms in hypercholesterolemic mice: role of serum cholesterol and temporal effects of exposure. PLoS One 9:e84517|
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