"The PhenX Toolkit-Standard Measures for Genomics Research" will maintain and expand the PhenX Toolkit to meet the evolving needs of the scientific community. The Toolkit currently includes 21 research domains, and 7 collections of measures related to Substance Abuse and Addiction. The Toolkit has a broad user base, and PhenX measures are being included in ongoing studies. The goals of the proposed work are to address four new research domains, to implement a rolling review and update of the 21 research domains, to integrate Chinese and Spanish translations of Toolkit protocols, to expand into social media, to build on our collaboration with the database of Genotypes and Phenotypes (dbGaP), and to make PhenX measures visible in all completed studies deposited in dbGaP. We will also foster collaborations with related measures efforts (e.g., the Patient Reported Outcomes Measurement Information System [PROMIS] and the National Institutes of Health [NIH] Toolbox), highlighting the complementary nature of these approaches and identifying synergies. Taken together, these efforts will attract additional users to the Toolkit and raise awareness of the Toolkit as an important, helpful resource for the scientific community. Widespread adoption of PhenX measures will facilitate cross-study analysis, thus increasing the scientific impact of individual studies. With continued support, PhenX will promote and advance collaborative research across the biomedical research community.

Public Health Relevance

The PhenX Toolkit-Standard Measures for Genomics Research proposes to maintain and expand the PhenX Toolkit to meet the evolving needs of the scientific community. This effort will raise awareness of the Toolkit as a valuable resource and attract additional users to the Toolkit. Widespread adoption of PhenX measures will facilitate cross-study analysis and thus increase the scientific impact of individual studies.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Biotechnology Resource Cooperative Agreements (U41)
Project #
1U41HG007050-01
Application #
8413285
Study Section
Ethical, Legal, Social Implications Review Committee (GNOM)
Program Officer
Ramos, Erin
Project Start
2013-07-01
Project End
2017-04-30
Budget Start
2013-07-01
Budget End
2014-04-30
Support Year
1
Fiscal Year
2013
Total Cost
$1,012,765
Indirect Cost
$369,808
Name
Research Triangle Institute
Department
Type
DUNS #
004868105
City
Research Triangle
State
NC
Country
United States
Zip Code
27709