Biosafety Fellowship Program. A strategic goal of the MRCE is to develop the region's biodefense infrastructure by training scientists to work with select and other infectious agents. The MRCE has established a career development program for a biosafety professional designed to meet the growing need for individuals capable of leading biosafety programs in government, industry, and academics. Biosafety Fellows participate in the day to day operations of a biosafety officer, and receive specialized training in all aspects of biosafety program development and management in the context of the MRCE consortium. Although supervised by Dr. Cook, fellows undergo rotations with select individuals to learn about specialized biosafety issues, including animal models of disease and working with pathogens at BSL3, with an emphasis on Select Agent Program management. Fellows assist with and participate in meetings of the Washington University Institutional Biological and Chemical Safety Committee (IBC) where they apply skills related to assessing risks associated with cutting-edge emerging infectious disease and biodefense research. Fellows also play a key role in the development of the MRCE Biosafety Education for the Research Scientist Course, aiding Dr. Cook in course management and participating as instructors and in the hands-on exercises. Professional Certification: At completion, fellows will have the opportunity to take the American Society for Microbiologists, National Registry of Microbiologists, Specialist in Biosafety certification exam. The MRCE will support the cost of this exam.

Public Health Relevance

A strategic goal of the NIAIDs biodefense initiative is to increase the nation's capacity to work safely on potentially dangerous human pathogens. The construction of several Regional and National Biocontainment labs are a direct outcome of this NIAID led initiative. This, along with specific funding opportunities offered be the RCE system for investigators to pursue biodefense and emerging infectious diseases research has led to a dramatic increase in BSL3 laboratory space. The MRCE Biosafety Fellowship is designed to meet the growing need for trained individuals capable of leading biosafety programs in these laboratories.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AI057160-09
Application #
8376783
Study Section
Special Emphasis Panel (ZAI1-DDS-M)
Project Start
Project End
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
9
Fiscal Year
2012
Total Cost
$97,411
Indirect Cost
$23,274
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Chen, Linxiao; Valentine, Jenny L; Huang, Chung-Jr et al. (2016) Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies. Proc Natl Acad Sci U S A 113:E3609-18
Ulland, Tyler K; Jain, Nidhi; Hornick, Emma E et al. (2016) Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nat Commun 7:13180
Miao, Chunhui; Li, Minghua; Zheng, Yi-Min et al. (2016) Cell-cell contact promotes Ebola virus GP-mediated infection. Virology 488:202-15
Zhao, Jincun; Vijay, Rahul; Zhao, Jingxian et al. (2016) MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis. J Virol 90:7098-108
Lubman, Olga Y; Fremont, Daved H (2016) Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. Structure 24:57-69
Markosyan, Ruben M; Miao, Chunhui; Zheng, Yi-Min et al. (2016) Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger. PLoS Pathog 12:e1005373
Grinnage-Pulley, Tara; Mu, Yang; Dai, Lei et al. (2016) Dual Repression of the Multidrug Efflux Pump CmeABC by CosR and CmeR in Campylobacter jejuni. Front Microbiol 7:1097
Teijaro, John R; Studer, Sean; Leaf, Nora et al. (2016) S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification. Proc Natl Acad Sci U S A 113:1351-6
Grinnage-Pulley, Tara; Zhang, Qijing (2015) Genetic Basis and Functional Consequences of Differential Expression of the CmeABC Efflux Pump in Campylobacter jejuni Isolates. PLoS One 10:e0131534
Nukui, Masatoshi; Mori, Yasuko; Murphy, Eain A (2015) A human herpesvirus 6A-encoded microRNA: role in viral lytic replication. J Virol 89:2615-27

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