It is generally recognized that the involvement of skilled biostatisticians is critical for the success of research in the medical sciences. Research that has as its intention the reduction ofthe burdens caused by the racial disparities in cancer incidence is no exception. For this reason, a Biostatistics Shared Resource (BSR) is an important part of this Partnership. For pilot/full projects, the BSR provides statistical consultation and collaborative support regarding study design, data management, and statistical analysis. The BSR also assists in the development of grant proposals and in the production of abstracts and manuscripts. In addition to its work supporting the research of Partnership investigators, the BSR works to enhance the biostatistical capabilities of the Partnership institutions. This is accomplished by providing biostatistical mentorship to junior investigators regarding sound applications of statistical principles to cancer research. We also participate in the Cancer Training Program and offer courses in biostatistics, epidemiology, clinical trials, and bioinformatics.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA118948-08
Application #
8759632
Study Section
Special Emphasis Panel (ZCA1-SRLB-Y (O1))
Project Start
2005-09-30
Project End
2016-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
8
Fiscal Year
2013
Total Cost
$33,480
Indirect Cost
$10,350
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Karthikeyan, Chandrabose; Lee, Crystal; Moore, Joshua et al. (2015) IND-2, a pyrimido[1?,2?:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells. Bioorg Med Chem 23:602-11
Samuel, Temesgen; Fadlalla, Khalda; Gales, Dominique N et al. (2014) Variable NF-?B pathway responses in colon cancer cells treated with chemotherapeutic drugs. BMC Cancer 14:599
Wells, Kristen J; Lima, Diana S; Meade, Cathy D et al. (2014) Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities. Eval Program Plann 44:14-25
Zhang, Huang-Ge; Grizzle, William E (2014) Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions. Am J Pathol 184:28-41
Richter, J R; Mahoney, M; Warram, J M et al. (2014) A dual-reporter, diagnostic vector for prostate cancer detection and tumor imaging. Gene Ther 21:897-902
Arora, Ritu; Yates, Clayton; Gary, Bernard D et al. (2014) Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer. PLoS One 9:e98370
Green, Hadiyah N; Crockett, Stephanie D; Martyshkin, Dmitry V et al. (2014) A histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression. Int J Nanomedicine 9:5093-102
Khazal, Kamel F; Hill, Donald L; Grubbs, Clinton J (2014) Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice. Anticancer Res 34:6327-32
Jones, Jacqueline; Wang, Honghe; Karanam, Balasubramanyam et al. (2014) Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas. Clin Exp Metastasis 31:497-510
Martin, Michelle Y; Fouad, Mona N; Oster, Robert A et al. (2014) What do cancer patients worry about when making decisions about treatment? Variation across racial/ethnic groups. Support Care Cancer 22:233-44

Showing the most recent 10 out of 55 publications