Core A: Administraton - The overall mission of the Administrative Core is to provide oversight, coordination, integration, global decision making, training, and leadership in coordinating the scientific, clinical, and financial aspects of this NTR Research Center. The Director for this Core is Thomas Wang, MD.PhD. He is also the Site Director at the University of Michigan, and will be intimately familiar with all aspects of standardization of the imaging protocols and clinical validation of fluorescent-labeled peptide, including proper function and calibration of the wide area endoscope and confocal microscope, concerns of the IRB and FDA, patient safety and logistical issues, and budget matters. Roy Soetikno, MD is the Core Co-Director at Stanford University, and will function as their Site Director. Kenneth Wang is also a Core Co-Director and is from the Mayo Clinic. He will be a representive on the NTR Steering Committee in addition to Dr. T Wang. The Directors of the Administrative Core will discuss the operations of the NTR Research Center at the regular Executive Committee meeting via teleconference on a bi-weekly basis. Implementation and follow up of action items will be performed by the Operations team, which includes 1) Don May, the NTR financial administrator at the University of Michigan, 2) Erin Shugard (University of Michigan), Christine Du (Stanford University), and Kelly Dunagan (Mayo Clinic), the CRAs at each respective site.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA136429-05
Application #
8381398
Study Section
Special Emphasis Panel (ZCA1-SRRB-9)
Project Start
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$48,123
Indirect Cost
$15,307
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Joshi, Bishnu P; Duan, Xiyu; Kwon, Richard S et al. (2016) Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia. Endoscopy 48:A1-A13
Joshi, Bishnu P; Pant, Asha; Duan, Xiyu et al. (2016) Multimodal Video Colonoscope for Targeted Wide-Field Detection of Nonpolypoid Colorectal Neoplasia. Gastroenterology 150:1084-6
Zhou, Juan; Joshi, Bishnu P; Duan, Xiyu et al. (2015) EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clin Transl Gastroenterol 6:e101
Khondee, Supang; Rabinsky, Emily F; Owens, Scott R et al. (2015) Targeted therapy of colorectal neoplasia with rapamycin in peptide-labeled pegylated octadecyl lithocholate micelles. J Control Release 199:114-21
Atreya, Raja; Neumann, Helmut; Neufert, Clemens et al. (2014) In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease. Nat Med 20:313-8
Qiu, Zhen; Khondee, Supang; Duan, Xiyu et al. (2014) Vertical cross-sectional imaging of colonic dysplasia in vivo with multi-spectral dual axes confocal endomicroscopy. Gastroenterology 146:615-7
Khondee, Supang; Wang, Thomas D (2013) Progress in molecular imaging in endoscopy and endomicroscopy for cancer imaging. J Healthc Eng 4:1-22
Liu, Zhongyao; Miller, Sharon J; Joshi, Bishnu P et al. (2013) In vivo targeting of colonic dysplasia on fluorescence endoscopy with near-infrared octapeptide. Gut 62:395-403
Sturm, Matthew B; Joshi, Bishnu P; Lu, Shaoying et al. (2013) Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results. Sci Transl Med 5:184ra61
Sevick-Muraca, Eva M; Akers, Walter J; Joshi, Bishnu P et al. (2013) Advancing the translation of optical imaging agents for clinical imaging. Biomed Opt Express 4:160-70

Showing the most recent 10 out of 35 publications