The PS-OC is committed to disseminate current and newly generated knowledge ofthe evolution, etiology, diagnosis and treatment of cancer. This is the basis for our educational program and outreach and dissemination initiatives. We will offer a rich program intended to enhance the interaction and training of physicians and scientist both regionally and at off-site facilities from regularly scheduled seminars to specific work groups. Video conferencing technology will be used for a target number of educafional lectures/didactic seminars in order for Pis and staff at our collaborative locations in CCNY and Vanderbilt to benefit. Opportunities to view web-casting's will also be made available to those external to our PS-OC with proper identification, login and feedback permitted. We have designed targeted programs for faculty, post-docs, graduate students and high school students to make an impact on a wide variety of people. Specifically, as part of our educafional program we will offer a unique Post-doctoral Training Program, a Course called

Public Health Relevance

The outreach and dissemination program ofthe PS-OC will ensure that the knowledge generated within the Center is disseminated to the community and other interested parties, and that evolutionary theory of cancer becomes accepted as a field of its own.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1-SRLB-9)
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Dana-Farber Cancer Institute
United States
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Han, Lin; Zi, Xiaoyuan; Garmire, Lana X et al. (2014) Co-detection and sequencing of genes and transcripts from the same single cells facilitated by a microfluidics platform. Sci Rep 4:6485
Dunn, Gavin P; Cheung, Hiu Wing; Agarwalla, Pankaj K et al. (2014) In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene. Proc Natl Acad Sci U S A 111:1102-7
Singh, Tanya; Kothapalli, Chandrasekhar; Varma, Devika et al. (2014) Carboxymethylcellulose hydrogels support central nervous system-derived tumor-cell chemotactic migration: comparison with conventional extracellular matrix macromolecules. J Biomater Appl 29:433-41
Meador, Catherine B; Micheel, Christine M; Levy, Mia A et al. (2014) Beyond histology: translating tumor genotypes into clinically effective targeted therapies. Clin Cancer Res 20:2264-75
Marusyk, Andriy; Tabassum, Doris P; Altrock, Philipp M et al. (2014) Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Nature 514:54-8
Foo, Jasmine; Michor, Franziska (2014) Evolution of acquired resistance to anti-cancer therapy. J Theor Biol 355:10-20
Tkach, Karen E; Oyler, Jennifer E; Altan-Bonnet, Grégoire (2014) Cracking the NF-?B code. Sci Signal 7:pe5
Guo, Shangqin; Zi, Xiaoyuan; Schulz, Vincent P et al. (2014) Nonstochastic reprogramming from a privileged somatic cell state. Cell 156:649-62
Leder, Kevin; Pitter, Ken; Laplant, Quincey et al. (2014) Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules. Cell 156:603-16
Elitas, Meltem; Brower, Kara; Lu, Yao et al. (2014) A microchip platform for interrogating tumor-macrophage paracrine signaling at the single-cell level. Lab Chip 14:3582-8

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