The PS-OC is committed to disseminate current and newly generated knowledge ofthe evolution, etiology, diagnosis and treatment of cancer. This is the basis for our educational program and outreach and dissemination initiatives. We will offer a rich program intended to enhance the interaction and training of physicians and scientist both regionally and at off-site facilities from regularly scheduled seminars to specific work groups. Video conferencing technology will be used for a target number of educafional lectures/didactic seminars in order for Pis and staff at our collaborative locations in CCNY and Vanderbilt to benefit. Opportunities to view web-casting's will also be made available to those external to our PS-OC with proper identification, login and feedback permitted. We have designed targeted programs for faculty, post-docs, graduate students and high school students to make an impact on a wide variety of people. Specifically, as part of our educafional program we will offer a unique Post-doctoral Training Program, a Course called

Public Health Relevance

The outreach and dissemination program ofthe PS-OC will ensure that the knowledge generated within the Center is disseminated to the community and other interested parties, and that evolutionary theory of cancer becomes accepted as a field of its own.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA143798-05
Application #
8566845
Study Section
Special Emphasis Panel (ZCA1-SRLB-9)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
5
Fiscal Year
2013
Total Cost
$34,721
Indirect Cost
$5,453
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Wala, Jeremiah A; Bandopadhayay, Pratiti; Greenwald, Noah F et al. (2018) SvABA: genome-wide detection of structural variants and indels by local assembly. Genome Res 28:581-591
Chakrabarti, Shaon; Michor, Franziska (2017) Pharmacokinetics and Drug Interactions Determine Optimum Combination Strategies in Computational Models of Cancer Evolution. Cancer Res 77:3908-3921
Wala, Jeremiah; Beroukhim, Rameen (2017) SeqLib: a C?++ API for rapid BAM manipulation, sequence alignment and sequence assembly. Bioinformatics 33:751-753
Amankulor, Nduka M; Kim, Youngmi; Arora, Sonali et al. (2017) Mutant IDH1 regulates the tumor-associated immune system in gliomas. Genes Dev 31:774-786
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Wala, Jeremiah; Zhang, Cheng-Zhong; Meyerson, Matthew et al. (2016) VariantBam: filtering and profiling of next-generational sequencing data using region-specific rules. Bioinformatics 32:2029-31
Amato, Katherine R; Wang, Shan; Tan, Li et al. (2016) EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res 76:305-18
Badri, H; Pitter, K; Holland, E C et al. (2016) Optimization of radiation dosing schedules for proneural glioblastoma. J Math Biol 72:1301-36

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