Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA151652-03
Application #
8309355
Study Section
Special Emphasis Panel (ZCA1-GRB-S (M1))
Program Officer
Grodzinski, Piotr
Project Start
2010-09-01
Project End
2015-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
3
Fiscal Year
2012
Total Cost
$2,484,269
Indirect Cost
$797,998
Name
University of North Carolina Chapel Hill
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Kim, Junghyun; Luo, Zhi-Xiang; Wu, Yue et al. (2017) In-Situ Formation of Holmium Oxide in Pores of Mesoporous Carbon Nanoparticles as Substrates for Neutron-Activatable Radiotherapeutics. Carbon N Y 117:92-99
Miao, Lei; Guo, Shutao; Lin, C Michael et al. (2017) Nanoformulations for combination or cascade anticancer therapy. Adv Drug Deliv Rev 115:3-22
Huo, Meirong; Zhao, Yan; Satterlee, Andrew Benson et al. (2017) Tumor-targeted delivery of sunitinib base enhances vaccine therapy for advanced melanoma by remodeling the tumor microenvironment. J Control Release 245:81-94
Kim, Junghyun; Narayan, Roger J; Lu, Xiuling et al. (2017) Neutron-activatable needles for radionuclide therapy of solid tumors. J Biomed Mater Res A 105:3273-3280
Min, Yuanzeng; Roche, Kyle C; Tian, Shaomin et al. (2017) Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy. Nat Nanotechnol 12:877-882
Goodwin, Tyler J; Huang, Leaf (2017) Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis. Vaccine 35:2550-2557
Satterlee, Andrew B; Attayek, Peter; Midkiff, Bentley et al. (2017) A dosimetric model for the heterogeneous delivery of radioactive nanoparticles In vivo: a feasibility study. Radiat Oncol 12:54
Tian, Xi; Nguyen, Minh; Foote, Henry P et al. (2017) CRLX101, a Nanoparticle-Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1?. Cancer Res 77:112-122
Goodwin, Tyler J; Shen, Limei; Hu, Mengying et al. (2017) Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival. Biomaterials 141:260-271
Kim, Junghyun; Jay, Michael (2017) Neutron-activatable radionuclide cancer therapy using graphene oxide nanoplatelets. Nucl Med Biol 52:42-48

Showing the most recent 10 out of 178 publications