The Program for the Elimination of Cancer Disparities (PECaD) at the Alvin J. Siteman Cancer Center, St Louis, MO of Washington University School of Medicine and Barnes-Jewish Hospital was established in 2003 with institutional funds in response to known excess cancer burden within the region particularly for minority and medically underserved populations. The Goals are to create a national model for eliminating disparities In cancer through community-based partnerships and community based participatory research (CBPR);to increase access by breaking down barriers to quality cancer care;and to be a catalyst for change in our region by fostering healthy communities. Given the fractured history of St Louis and its segregation, PECaD has worked with numerous community organizations and provider groups to build trust and has harnessed resources from non federal sources and NCI. We now propose to further strengthen partnerships in the St. Louis region and extend our activities to additional areas chosen based on poverty levels;limited access to cancer screening and prevention services;excess cancer incidence or mortality;and expressed community Interest In collaborative efforts to address cancer health disparities. Our three communities are St Louis City and North County, MO;St. Clair County, IL, and southeastern Missouri.
The Specific aims are: 1. In collaboration with our community partners, using the community outreach program and working with our community partnerships, we will extend and evaluate the effectiveness of outreach. 2. In a research project created in partnership with our colorectal cancer community partnership, we will design and conduct a RCT of community awareness plus systems level changes to reinforce provider behavior change to order and follow-up on colorectal cancer screening tests. 3. In our pilot educational research project created with our prostate cancer community partnership, we will evaluate barriers and facilitators to participation in prostate CA tissue collection for research (biobanking). 4. Through our training program, provide CBPR training for researchers and community members collaborating with the program and institute an ongoing process for Identifying and vetting future pilot projects. 5. In conjunction with our community Disparities Elimination Advisory Committee (DEAC), we will develop a framework for evaluation within and across our Community Outreach, Research, and Training Programs.

Public Health Relevance

Excess cancer mortality In low income, minority and underserved populations will be addressed through community based participatory research projects that bring prevention information and access to 3 high risk populations. In addition a research project addressing disparities in access to colorectal cancer screening will be Implemented and evaluated along with education and training program s to Increase expertise among junior investigators addressing cancer health disparities.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1-PCRB-G (M1))
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Banez, Lionel L
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Washington University
Schools of Medicine
Saint Louis
United States
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Connors, Shahnjayla K; Goodman, Melody S; Noel, Lailea et al. (2015) Breast cancer treatment among African American women in north St. Louis, Missouri. J Urban Health 92:67-82
Hartz, Sarah M; Olfson, Emily; Culverhouse, Robert et al. (2015) Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change. Genet Med 17:374-9
Thompson, Vetta L Sanders; Drake, Bettina; James, Aimee S et al. (2015) A Community Coalition to Address Cancer Disparities: Transitions, Successes and Challenges. J Cancer Educ 30:616-22
Johnson, Kimberly J; Gehlert, Sarah (2014) Return of Results from Genomic Sequencing: A Policy Discussion of Secondary Findings for Cancer Predisposition. J Cancer Policy 2:75-80
Griffey, Richard T; Kennedy, Sarah K; D'Agostino McGowan, Lucy et al. (2014) Is low health literacy associated with increased emergency department utilization and recidivism? Acad Emerg Med 21:1109-15
Boeke, Caroline E; Tamimi, Rulla M; Berkey, Catherine S et al. (2014) Adolescent carotenoid intake and benign breast disease. Pediatrics 133:e1292-8
Caito, Nikki; Hood, Sula; Thompson, Vetta L Sanders (2014) Discussing cancer: communication with African Americans. Soc Work Health Care 53:519-31
Morgan, Tamandra; Schmidt, Johanna; Haakonsen, Christy et al. (2014) Using the internet to seek information about genetic and rare diseases: a case study comparing data from 2006 and 2011. JMIR Res Protoc 3:e10
Gehlert, Sarah (2014) Forging an integrated agenda for primary cancer prevention during midlife. Am J Prev Med 46:S104-9
Liu, Ying; Colditz, Graham A; Gehlert, Sarah et al. (2014) Racial disparities in risk of second breast tumors after ductal carcinoma in situ. Breast Cancer Res Treat 148:163-73

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