Project title: Racial Disparities in Depression and Mental Healthcare Utilization in Lung Cancer Principle Investigators: Sheila Cannon (UMB) and Elyse Park (DF/HCC) Abstract: Psychosocial problems associated with cancer care are often unaddressed, particularly related to lung cancer, which has been found to elevate risk for psychological distress relative to other cancers. Psychosocial problems can cause additional suffering, weaken adherence to prescribed treatments, and lead to increased lung cancer mortality^ independent of clinical factors. African American (AA) lung cancer patients may be particulariy vulnerable to psychosocial problems in cancer care due to a range of issues, including access to care and other bamers. In Phase 1 of this study we will utilize a nationally representative dataset from the Cancer Care Outcomes Research &Surveillance (CanCORS) Consortium to compare prevalence of depression symptoms, factors underiying depression symptoms, and rates of mental healthcare utilization in 2108 AA and NHW lung cancer patients. We will also examine effect of cancer care experiences on depression severity at 4-months post-diagnosis. This will be the first study to conduct these analyses using a population-based approach. Data is available from patients, physicians, and medical records, and thus we will be able to test for racial disparities, adjusting for relevant demographic, medical, institutional and social/ behavioral factors. We expect to confirm some of our assumptions and generate new questions about risks and protective factors that quantitative data cannot address. Therefore, Phase 2 will include in-depth qualitative assessments of beliefs about depression and mental healthcare seeking in AA and NHW lung cancer patients at Massachusetts General Hospital. This proposed pilot project represents an innovative effort to address racial disparities in mental healthcare services, which is an understudied aspect of cancer care. The team for this mixed methods study, led by Dr. Elyse Park of DF/HCC and Dr. Sheila Cannon of UMB are well-poised to conduct this study, which will contribute significantly to their career development Both the Survey and Statistical Methods Core and Training Core will significantly contribute to this project.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-SRLB-3)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Dana-Farber Cancer Institute
United States
Zip Code
Tucker-Seeley, Reginald D; Abel, Gregory A; Uno, Hajime et al. (2015) Financial hardship and the intensity of medical care received near death. Psychooncology 24:572-8
Underhill, Meghan L; Crotser, Cheryl B (2014) Seeking balance: decision support needs of women without cancer and a deleterious BRCA1 or BRCA2 mutation. J Genet Couns 23:350-62
Garrido, Melissa M; Penrod, Joan D; Prigerson, Holly G (2014) Unmet need for mental health care among veterans receiving palliative care: assessment is not enough. Am J Geriatr Psychiatry 22:540-4
Leyva, Bryan; Allen, Jennifer D; Tom, Laura S et al. (2014) Religion, fatalism, and cancer control: a qualitative study among Hispanic Catholics. Am J Health Behav 38:839-49
McKeown, Michael R; Shaw, Daniel L; Fu, Harry et al. (2014) Biased multicomponent reactions to develop novel bromodomain inhibitors. J Med Chem 57:9019-27
Vetter, Michael L; Zhang, Zijuan; Liu, Shuai et al. (2014) Fluorescent visualization of Src by using dasatinib-BODIPY. Chembiochem 15:1317-24
Enzinger, Andrea C; Zhang, Baohui; Weeks, Jane C et al. (2014) Clinical trial participation as part of end-of-life cancer care: associations with medical care and quality of life near death. J Pain Symptom Manage 47:1078-90
Negrón, Rosalyn; Leyva, Bryan; Allen, Jennifer et al. (2014) Leadership networks in Catholic parishes: implications for implementation research in health. Soc Sci Med 122:53-62
Wright, Alexi A; Zhang, Baohui; Keating, Nancy L et al. (2014) Associations between palliative chemotherapy and adult cancer patients' end of life care and place of death: prospective cohort study. BMJ 348:g1219
Traeger, Lara; Cannon, Sheila; Keating, Nancy L et al. (2014) Race by sex differences in depression symptoms and psychosocial service use among non-Hispanic black and white patients with lung cancer. J Clin Oncol 32:107-13

Showing the most recent 10 out of 27 publications