With the support of P20 EXPORT NCCU Center for Excellence, we have designated space and basic instruments to establish a Diagnostic and Molecular Histopathology Facility (DMHF) at the Julius L. Chambers Biomedical/Biotechnology Research Institute (BBRI) of the North Carolina Central University (NCCU). In this U54 partnership between NCCU and Lineberger Comprehensive Cancer Center (LCCC), our DMHF has Specific Aims as follows: (1) To further develop a diagnostic and molecular histopathology laboratory;(2) To provide histopathological service to research projects in this grant proposal and other health disparity studies;(3) To support publications and grant applications when histopathology expertise is needed;and (4) To train students, postdocs and technical staff members to use histopathological techniques for both research and educational purposes. In summary, the DMHF is expected to provide solid technical support to research projects, training and education during the U54 grant period and in the future. The goal is to ensure the partnership in cancer disparity research among NCCU and LCCC a success.

National Institute of Health (NIH)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of North Carolina Chapel Hill
Chapel Hill
United States
Zip Code
Linnan, Laura A; D'Angelo, Heather; Harrington, Cherise B (2014) A literature synthesis of health promotion research in salons and barbershops. Am J Prev Med 47:77-85
Ren, Dongren; Zheng, Gaolin; Bream, Susan et al. (2014) Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus. Dig Dis Sci 59:57-63
Galbraith, Kayoll V; Gilkey, Melissa B; Smith, Jennifer S et al. (2014) Perceptions of mailed HPV self-testing among women at higher risk for cervical cancer. J Community Health 39:849-56
Chen, Hao; Hu, Yuhui; Fang, Yu et al. (2014) Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium. Gut 63:711-9
Raghuwanshi, Sandeep K; Smith, Nikia; Rivers, Elizabeth J et al. (2013) G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol 190:5329-36
Orman, Eric S; Li, Nan; Shaheen, Nicholas J (2013) Efficacy and durability of radiofrequency ablation for Barrett's Esophagus: systematic review and meta-analysis. Clin Gastroenterol Hepatol 11:1245-55
Fang, Yu; Chen, Hao; Hu, Yuhui et al. (2013) Gastroesophageal reflux activates the NF-?B pathway and impairs esophageal barrier function in mice. Am J Physiol Gastrointest Liver Physiol 305:G58-65
Jovov, Biljana; Shaheen, Nicholas J; Orlando, Geraldine S et al. (2013) Defective barrier function in neosquamous epithelium. Am J Gastroenterol 108:386-91