The Clinical Trials Core has been active since the initiation of the U54 and has systematically and progressively advanced by sustaining, improving and extending its basic mission. The Core contributes to 1) patient targeting especially minority and underserved accrual on cancer clinical trials, 2) education of hematology/oncology fellows and 3) research into the issues of the minority and underserved patient with cancer. Overall, the Core has entered large numbers of minority and underserved patients onto clinical trials and given these patients opportunities that are usually not available at fail-safe public hospitals. The Core maintains a complete resource for clinical trials including administrative support, IRB support, data collection and management, patient navigation, research nursing support and secretarial assistance. Prior to U54 support, 6 patients were entered on clinical trials at the NGH. In distinction, over the history of the Core, we have accrued 638 patients to clinical trials of which approximately 50% are minorities (African American and Hispanic). The overall accrual rate is 22% of all patients screened. The accrual rate of patients who had a study available for their disease site and stage and who met eligibility criteria is a remarkatjie 53%. At our site, minority patients are no less likely to consent to clinical trials compared to majority patients.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163072-02
Application #
8380464
Study Section
Special Emphasis Panel (ZCA1-SRLB-Y)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
2
Fiscal Year
2012
Total Cost
$254,293
Indirect Cost
$91,285
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Hull, Pamela; Emerson, Janice S; Quirk, Meghan E et al. (2017) A Smartphone App for Families With Preschool-Aged Children in a Public Nutrition Program: Prototype Development and Beta-Testing. JMIR Mhealth Uhealth 5:e102
Schlundt, David; Briley, Chiquita; Canada, Barbara et al. (2017) Availability of Low-Fat Milk and Produce in Small and Mid-Sized Grocery Stores After 2014 WIC Final Rule Changes, Tennessee. Prev Chronic Dis 14:E70
Uzhachenko, Roman; Boyd, Kelli; Olivares-Villagomez, Danyvid et al. (2017) Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) 9:627-649
Brown, Shyretha; Tehrani, Shahin; Whalen, Margaret M (2017) Dibutyltin-induced alterations of interleukin 1beta secretion from human immune cells. J Appl Toxicol 37:181-191
Amara, Suneetha; Tiriveedhi, Venkataswarup (2017) The Five Immune Forces Impacting DNA-Based Cancer Immunotherapeutic Strategy. Int J Mol Sci 18:
Selove, Rebecca; Foster, Maya; Wujcik, Debra et al. (2017) Psychosocial concerns and needs of cancer survivors treated at a comprehensive cancer center and a community safety net hospital. Support Care Cancer 25:895-904
Sanderson, Maureen; Canedo, Juan R; Khabele, Dineo et al. (2017) Pragmatic trial of an intervention to increase human papillomavirus vaccination in safety-net clinics. BMC Public Health 17:158
Ho, Meng-Hsuan; Lamont, Richard J; Xie, Hua (2017) Identification of Streptococcus cristatus peptides that repress expression of virulence genes in Porphyromonas gingivalis. Sci Rep 7:1413
Selove, Rebecca; Foster, Maya; Mack, Raquel et al. (2017) Using an Implementation Research Framework to Identify Potential Facilitators and Barriers of an Intervention to Increase HPV Vaccine Uptake. J Public Health Manag Pract 23:e1-e9
Hull, P C; Buchowski, M; Canedo, J R et al. (2016) Childhood obesity prevention cluster randomized trial for Hispanic families: outcomes of the healthy families study. Pediatr Obes :

Showing the most recent 10 out of 90 publications