PCIPS CORE SUPPORT The PCIPS will be supported by three cores: the Screening Process Documentation Unit, the Biostatistics Core, and the Administrative Core, each described briefly below Screening Process Documentation Unit: The foundation of the PCIPS is the Screening Process Documentation Unit (SPDU), an innovative data core that integrates data from a range of sources to create a comprehensive picture of the screening process across a diverse population of women in the Delaware Valley. This comprehensive picture includes longitudinal information about the screening process as well as multi-level information about the systems in which women are seen and the communities in which they live. By pulling these data together into a cohesive whole (entitled the Breast Screening Data Repository or BSDR) (Figure 2), insight can be gained into the determinants of screening outcomes across a population, and perhaps even more importantly, into where this process can be improved.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163313-04
Application #
8715729
Study Section
Special Emphasis Panel (ZCA1-SRLB-R)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
4
Fiscal Year
2014
Total Cost
$249,860
Indirect Cost
$109,456
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Onega, Tracy; Beaber, Elisabeth F; Sprague, Brian L et al. (2014) Breast cancer screening in an era of personalized regimens: a conceptual model and National Cancer Institute initiative for risk-based and preference-based approaches at a population level. Cancer 120:2955-64
Keller, Brad M; Chen, Jinbo; Conant, Emily F et al. (2014) Breast density and parenchymal texture measures as potential risk factors for Estrogen-Receptor positive breast cancer. Proc SPIE Int Soc Opt Eng 9035:90351D
McCarthy, Anne Marie; Kontos, Despina; Synnestvedt, Marie et al. (2014) Screening outcomes following implementation of digital breast tomosynthesis in a general-population screening program. J Natl Cancer Inst 106:
McCarthy, Anne Marie; Armstrong, Katrina (2014) The role of testing for BRCA1 and BRCA2 mutations in cancer prevention. JAMA Intern Med 174:1023-4
Conant, Emily F (2014) Clinical implementation of digital breast tomosynthesis. Radiol Clin North Am 52:499-518
Keller, Brad M; Nathan, Diane L; Gavenonis, Sara C et al. (2013) Reader variability in breast density estimation from full-field digital mammograms: the effect of image postprocessing on relative and absolute measures. Acad Radiol 20:560-8
Daye, Dania; Keller, Brad; Conant, Emily F et al. (2013) Mammographic parenchymal patterns as an imaging marker of endogenous hormonal exposure: a preliminary study in a high-risk population. Acad Radiol 20:635-46