The overall goal of the Mentoring and Training Core (Core B) is to leverage the commitment and capabilities of the Ugandan clinical research scientists from our previous training programs to build a sustainable, mutually supportive, cadre of independent opinion leaders and mentors for cancer research progress.
Specific Aim 1 will provide intensive leadership and skills training to the three Ugandan Co-leaders of Projects 1,2,3. These three """"""""Senior Fellows"""""""" will spend two one-month periods in Seattle for this training.
Specific Aim 2 expands a novel peer mentoring career development (PMCD) program that includes the Senior Fellows and 15-16 additional Medical Officers and key personnel on Hutchinson Center Research Institute of Uganda (HCRI-Uganda) projects.
Specific Aim 3 will build a Biomedical Research Integrity (BRI) program that extends current mandatory training and ties in to Makerere University's College of Health Sciences (MakCHS) professionalism development programs. Senior Fellows will assume substantial responsibility for activities within each of the three Aims: 1) Senior fellows will be accountable for team building and communications for the Uganda-based activities of their respective Projects. 2) Senior Fellows will take increasing roles in facilitating weekly meetings of the PMCD group and will join the roster of expert, local consultants who provide presentations for the peer mentees and others in the scientific community. 3) They will form a committee to draft a request for applications (RFA) and critique submissions for two pilot research projects and will serve as an oversight committee for the awarded projects. 4) Senior Fellows will also form the core of the Scientific Organizing Committee for the second regional Clinical Research Career Development Symposium to be held in Year 5. 5) A Senior Fellow will serve as Research Integrity Officer to counsel scientists and staff in the HCRI-Ug BRI and participate in BRI trainings. Experiential """"""""learning by doing"""""""" within the mentored environment of Core B will accelerate progress toward independence by the Senior Fellows and, by their leadership in the PMCD and BRI programs, will assist in the development of others in the HCRI-Uganda program and the wider community.

Public Health Relevance

Junior scientists hold the key to the research, medical training, and public health policy development that will improve health care delivery and provide prevention programs to fight cancer in Uganda. Intensive training in leadership, team building, management, and mentoring is proposed to give new clinician-scientists there the skills to start successful, independent programs. The current professional skills and research ethics training programs will be expanded to benefit both the trainees and the broader scientific community.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54CA190146-01
Application #
8926073
Study Section
Special Emphasis Panel (ZCA1-RPRB-O (M2))
Program Officer
Dominguez, Geraldina
Project Start
Project End
Budget Start
2014-09-17
Budget End
2015-07-31
Support Year
1
Fiscal Year
2014
Total Cost
$41,463
Indirect Cost
$11,777
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Beima-Sofie, Kristin; Wamalwa, Dalton; Maleche-Obimbo, Elizabeth et al. (2018) Toll-like receptor 9 polymorphism is associated with increased Epstein-Barr virus and Cytomegalovirus acquisition in HIV-exposed infants. AIDS 32:267-270
Coghill, Anna E; Schenk, Jeannette M; Mahkoul, Zeina et al. (2018) Omega-3 decreases IL-6 levels in HIV and human herpesvirus-8 coinfected patients in Uganda. AIDS 32:505-512
Menon, Manoj P; Coghill, Anna; Mutyaba, Innocent O et al. (2018) Association Between HIV Infection and Cancer Stage at Presentation at the Uganda Cancer Institute. J Glob Oncol :1-9
Bender Ignacio, Rachel; Ghadrshenas, Matine; Low, Daniel et al. (2018) HIV Status and Associated Clinical Characteristics Among Adult Patients With Cancer at the Uganda Cancer Institute. J Glob Oncol :1-10
Phipps, Warren; Kansiime, Rachel; Stevenson, Philip et al. (2018) Peer Mentoring at the Uganda Cancer Institute: A Novel Model for Career Development of Clinician-Scientists in Resource-Limited Settings. J Glob Oncol :1-11
Low, Daniel; Merkel, Emily C; Menon, Manoj et al. (2017) Chemotherapy Use at the End of Life in Uganda. J Glob Oncol 3:711-719
Coghill, Anna E; Schenk, Jeanette M; Mahkoul, Zeina et al. (2017) Omega-3 decreases interleukin-6 levels in HIV and HHV-8 co-infected patients: results from a randomized supplementation trial in Uganda. AIDS :
Okuku, Fred; Krantz, Elizabeth M; Kafeero, James et al. (2017) Evaluation of a Predictive Staging Model for HIV-Associated Kaposi Sarcoma in Uganda. J Acquir Immune Defic Syndr 74:548-554
Casper, Corey; Fitzmaurice, Christina (2016) Infection-related cancers: prioritising an important and eliminable contributor to the global cancer burden. Lancet Glob Health 4:e580-1