The Biostatistics Core provides comprehensive data processing and analysis services for the Specialized Research Center (P50), on """"""""Evaluating New Nicotine Standards for Cigarettes"""""""". These include form design, study design, and statistical analysis. These services will be provided to investigators and leaders of the four main projects in the proposed specialized research center, as well as to Cores A and B if necessary. The Core director. Dr. Chap Le, and Core co-director. Dr. Xianghua Luo, who will manage and direct the Core, have extensive experience in the areas of biostatistics and tobacco research and also manage many similar large projects in the Biostatistics and Bioinformatics Core of the University of Minnesota Comprehensive Cancer Center. Statistical expertise in the Core is particularly noteworthy in regard to the projects proposed for this P50 which include several randomized trials. It is believed that this group will be an important and essential asset to investigators of this specialized research center.

Public Health Relevance

The goal of the Biostatistics Core, Core C, is to support and promote high quality, team-oriented, and transdisciplinary research on tobacco evaluation as proposed in this grant application. The Core will be responsible for assisting the Project Leaders in study design, data collection and processing, quality control, data storage and retrieval, and statistical data analysis.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54DA031659-04
Application #
8710135
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
Pacek, Lauren R; Vandrey, Ryan; Dermody, Sarah S et al. (2016) Evaluation of a reduced nicotine product standard: Moderating effects of and impact on cannabis use. Drug Alcohol Depend 167:228-32
Perkins, Kenneth A; Kunkle, Nicole; Karelitz, Joshua L et al. (2016) Threshold dose for discrimination of nicotine via cigarette smoking. Psychopharmacology (Berl) 233:2309-17
Smith, Tracy T; Cassidy, Rachel N; Tidey, Jennifer W et al. (2016) Impact of smoking reduced nicotine content cigarettes on sensitivity to cigarette price: Further results from a multi-site clinical trial. Addiction :
von Weymarn, Linda B; Thomson, Nicole M; Donny, Eric C et al. (2016) Quantitation of the Minor Tobacco Alkaloids Nornicotine, Anatabine, and Anabasine in Smokers' Urine by High Throughput Liquid Chromatography-Mass Spectrometry. Chem Res Toxicol 29:390-7
Nardone, Natalie; Donny, Eric C; Hatsukami, Dorothy K et al. (2016) Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. Addiction :
Dermody, Sarah S; Tidey, Jennifer W; Denlinger, Rachel L et al. (2016) The Impact of Smoking Very Low Nicotine Content Cigarettes on Alcohol Use. Alcohol Clin Exp Res 40:606-15
Tidey, Jennifer W (2016) A behavioral economic perspective on smoking persistence in serious mental illness. Prev Med 92:31-35
Smith, Tracy T; Rupprecht, Laura E; Cwalina, Samantha N et al. (2016) Effects of Monoamine Oxidase Inhibition on the Reinforcing Properties of Low-Dose Nicotine. Neuropsychopharmacology 41:2335-43
Guillot, Casey R; Stone, Matthew D; Geary, Bree A et al. (2015) Pharmacological, sensorimotor, and expectancy effects on tobacco withdrawal: a preliminary study. Hum Psychopharmacol 30:364-71
Tidey, Jennifer W; Miller, Mollie E (2015) Smoking cessation and reduction in people with chronic mental illness. BMJ 351:h4065

Showing the most recent 10 out of 30 publications