The Biostatistics, Epidemiology, and Research Design (BERD) Key Component Activities (KCA) include the application of biostatistics, epidemiology and informatics advanced methods to the research design, conduct, and analysis of state-of-the-art laboratory, clinical and community-based studies. The BERD provides expertise, collaborative support and training through the Oklahoma Shared Clinical and Translational Resources (OSCTR) to students, trainees, faculty members and health care professionals at all of the institutions that are part of this proposal. Those include the seven colleges at the University of Oklahoma Health Sciences Center (OUHSC), OU-Norman, OU-Tulsa, Oklahoma Medical Research Foundation (OMRF), Veteran's Affairs Medical Center, Oklahoma State Health Department, Chickasaw Nation, Cherokee Nation, Choctaw Nation, Oklahoma City Indian Clinic, , Medical University of South Carolina, University of Arkansas Health Sciences Center and the American Indian tribal health centers from the 38 federally recognized tribes in Oklahoma and Kansas. Members of the BERD will integrate the disciplines of biostatistics, epidemiology, and informatics with other OSCTR activities to facilitate the development and evaluation of disease prevention, diagnosis, and treatment approaches to improve health and health outcomes in Oklahoma and partnering IDeA states. The OSCTR activities will include basic medical science laboratory research, preclinical studies, randomized controlled clinical trials, translational studies and community-based studies, which are aimed at improving the understanding of disease processes and their related risk factors, evaluating the validity of innovative diagnostic methods, estimating the efficacy and effectiveness of potential therapeutics and enhancing the adoption of best treatment and prevention strategies in the community. The BERD KCA will build on existing efforts of the OUHSC Department of Biostatistics and Epidemiology and OMRF to organize biostatistics, epidemiology and informatics resources in the OSCTR. It will enhance these efforts by providing an umbrella organization to bring together a diversity of campus resources in biostatistics, epidemiology, and informatics into a single entity. This concentrated focus of research design and analysis expertise will greatly facilitate research quality, productivity and the translation of research findings to practice in the community/population.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54GM104938-01A1
Application #
8608745
Study Section
Special Emphasis Panel (ZGM1-TWD-C (CC))
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-06-30
Support Year
1
Fiscal Year
2013
Total Cost
$573,846
Indirect Cost
$163,086
Name
University of Oklahoma Health Sciences Center
Department
Type
DUNS #
878648294
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
Rostaminia, Ghazaleh; Peck, Jennifer D; Quiroz, Lieschen H et al. (2016) Characteristics associated with pelvic organ prolapse in women with significant levator ani muscle deficiency. Int Urogynecol J 27:261-7
Munroe, Melissa E; Young, Kendra A; Kamen, Diane L et al. (2016) Soluble Mediators and Clinical Features Discern Risk of Transitioning to Classified Disease in Relatives of Systemic Lupus Erythematosus Patients. Arthritis Rheumatol :
Sandhya, Pulukool; Kurien, Biji Theyilamannil; Danda, Debashish et al. (2016) Update on Pathogenesis of Sjögren's syndrome. Curr Rheumatol Rev :
Rabadi, Meheroz H; Aston, Christopher E (2016) Compare serum creatinine versus Renal (99m)Tc-DTPA scan determined glomerular filtration rates in veterans with traumatic spinal cord injury and meurogenic bladder. J Spinal Cord Med 39:638-644
Young, Kendra A; Munroe, Melissa E; Guthridge, Joel M et al. (2016) Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis :
Hannafon, Bethany N; Trigoso, Yvonne D; Calloway, Cameron L et al. (2016) Plasma exosome microRNAs are indicative of breast cancer. Breast Cancer Res 18:90
Heu, May Kou; Welborn, Toney; Nagykaldi, Zsolt (2016) Clinical Question: In adult patients on warfarin, does-home-self-testing of prothrombin time and/or international normalized ratio provide the same outcomes compared to testing by a home health nurse or in a clinical setting? J Okla State Med Assoc 109:99-100
Wolska, Nina; Rybakowska, Paulina; Rasmussen, Astrid et al. (2016) Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity. Arthritis Rheumatol 68:724-9
Lu, Rufei; Munroe, Melissa E; Guthridge, Joel M et al. (2016) Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies. J Autoimmun 74:182-193
Bonney, Phillip A; Maurer, Adrian J; Cheema, Ahmed A et al. (2016) Clinical significance of changes in pB-C2 distance in patients with Chiari Type I malformations following posterior fossa decompression: a single-institution experience. J Neurosurg Pediatr 17:336-42

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