Abstract

The Administrative Core of the Boston Children's Hospital / Harvard Medical School IDDRC enhances research and promotes the development of new therapies by supporting outstanding research focused on problems relevant to intellectual and developmental disabilities. The Core supports the financial and administrative management of core facilities, provides core services to aid in the training of young investigators and their trainees, and fosters overall ?centerness? to enhance and encourage collaboration between IDDRC investigators. Through active engagement with other IDDRC cores and investigators throughout the national IDDRC network, the core services provided by our IDDRC promote collaboration outside the institution to speed the development of effective clinical interventions in intellectual and developmental disabilities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54HD090255-01
Application #
9229197
Study Section
Special Emphasis Panel (ZHD1-DSR-H (50))
Project Start
2016-09-23
Project End
2021-05-31
Budget Start
2016-09-01
Budget End
2017-05-31
Support Year
1
Fiscal Year
2016
Total Cost
$158,101
Indirect Cost
$68,779

  Institution

Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Yuskaitis, Christopher J; Jones, Brandon M; Wolfson, Rachel L et al. (2018) A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiol Dis 111:91-101
Smith, Lois E H; Hellström, Ann; Stahl, Andreas et al. (2018) Development of a Retinopathy of Prematurity Activity Scale and Clinical Outcome Measures for Use in Clinical Trials. JAMA Ophthalmol :
Gao, Xue; Tao, Yong; Lamas, Veronica et al. (2018) Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature 553:217-221
Fu, Zhongjie; Löfqvist, Chatarina A; Liegl, Raffael et al. (2018) Photoreceptor glucose metabolism determines normal retinal vascular growth. EMBO Mol Med 10:76-90
Latremoliere, Alban; Cheng, Long; DeLisle, Michelle et al. (2018) Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep 24:1865-1879.e9
Lodato, Michael A; Rodin, Rachel E; Bohrson, Craig L et al. (2018) Aging and neurodegeneration are associated with increased mutations in single human neurons. Science 359:555-559
Beggs, Alan H; Byrne, Barry J; De Chastonay, Sabine et al. (2018) A multicenter, retrospective medical record review of X-linked myotubular myopathy: The recensus study. Muscle Nerve 57:550-560
Asai, Yukako; Pan, Bifeng; Nist-Lund, Carl et al. (2018) Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1. Sci Rep 8:12124
Modi, Meera E; Sahin, Mustafa (2018) A unified circuit for social behavior. Neurobiol Learn Mem :
Hrvatin, Sinisa; Hochbaum, Daniel R; Nagy, M Aurel et al. (2018) Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex. Nat Neurosci 21:120-129

Showing the most recent 10 out of 498 publications