The goal of the proposed U54 RCTR grant is to assure that the RMATRIX-II infrastructure supports the further development of the Community of (clinical and translational health disparities) Investigators in Hawaii. Specifically, the aimsare to: (1) Foster clinical and translational health disparities research;(2) Build institutional and community research synergy;and (3) Advance the career development and mentoring of health disparities investigators. Overall, RMATRIX-II will provide an integrated research infrastructure that is connected with various University units, RTRN sites, and the grass-roots community in Hawaii. RMATRIX-II will address these aims as follows:
Specific Aim 1 : RMATRIX-II will provide tools (e.g., pilot projects and integrated research Cores) to foster clinical and translational health disparities research by investigators with skills in basic, clinical and polic research.
Specific Aim 2 : RMATRIX-II will foster collaborations and partnerships among disciplines, departments and/or schools/colleges of UHM, between institutions and with the community.
Specific Aim 3 : RMATRIX-II will foster career development and mentorship using synergistic research cores and a Navigator program to develop junior investigators, especially those with an interest in community based participatory research.

Public Health Relevance

RMATRIX-II will provide the tools needed to build translational research synergy, foster intra- and inter-institutional collaborations and partnerships, and build a Community of Investigators addressing health disparities in Hawaii. Such research infrastructure is invaluable not only for addressing significant existing health disparities, but also for achieving opportunity for the development of skilled investigators from Hawaii.

Agency
National Institute of Health (NIH)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54MD007584-04
Application #
8751381
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Wasserman, Joan
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Hawaii
Department
None
Type
Schools of Medicine
DUNS #
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Sentell, Tetine; Miyamura, Jill; Ahn, Hyeong Jun et al. (2015) Potentially Preventable Hospitalizations for Congestive Heart Failure Among Asian Americans and Pacific Islanders in Hawai'i. J Immigr Minor Health 17:1289-97
Sentell, Tetine; Chang, Ann; Cheng, Yongjun et al. (2014) Maternal quality and safety outcomes for Asians and Pacific Islanders in Hawai'i: an observational study from five years of statewide data. BMC Pregnancy Childbirth 14:298
Sentell, Tetine; Marten, Lisa; Ahn, Hyeong Jun et al. (2014) Disparities in hospitalizations among HIV positive individuals for Native Hawaiians and Asians compared to Whites in Hawai'i. Hawaii J Med Public Health 73:308-14
Kottschade, Lisa A; Grotz, Travis E; Dronca, Roxana S et al. (2014) Rare presentations of primary melanoma and special populations: a systematic review. Am J Clin Oncol 37:635-41
Sullivan, Katherine; Shikuma, Cecilia M; Chow, Dominic et al. (2014) Aerobic fitness levels and validation of a non exercise VO2max prediction equation for HIV-infected patients on HAART. HIV Clin Trials 15:69-77
Stotzer, Rebecca L; Ka'opua, Lana Sue I; Diaz, Tressa P (2014) Is healthcare caring in Hawai'i? Preliminary results from a health assessment of lesbian, gay, bisexual, transgender, questioning, and intersex people in four counties. Hawaii J Med Public Health 73:175-80
Juarez, Deborah T; Tan, Candace; Davis, James W et al. (2014) Using quantile regression to assess disparities in medication adherence. Am J Health Behav 38:53-62
Ka'opua, Lana Sue I; Diaz, Tressa P; Park, Soon H et al. (2014) Colorectal Cancer Screening at the Nexus of HIV, Minority Statuses, and Cultural Safety. Am J Health Educ 45:42-51
Shikuma, Cecilia M; Barbour, Jason D; Ndhlovu, Lishomwa C et al. (2014) Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-* levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors. AIDS Res Hum Retroviruses 30:142-6
Ndhlovu, Lishomwa C; Umaki, Tracie; Chew, Glen M et al. (2014) Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associa J Neurovirol 20:571-82

Showing the most recent 10 out of 62 publications