The Administrative Core will be critical in providing overall leadership and central administrative supportto the Chemistry Center, including establishing and implementing, in collaboration with center staff, assayproviders and the NIH Network Science Officer, a Compound Probe Development Plan (CPDP) for eachprogram. One of the most critical functions of the Administrative Core will be communication with otherCenters within the MLPCN, including coordination of studies, transfer of compounds, and efficientcommunication of data to facilitate iterative compound synthesis and testing. In addition, the AdministrativeCore will be responsible for organization for all Center meetings, travel arrangements for attendance ofMLPCN meetings, preparation of progress reports and noncompetitive renewal applications. Finally, theadministrative core will be responsible for recruitment and staffing as well as budgetary management of theProgram. The following specific aims summarize the major functions of the administrative core:
AIM 1. To establish goals of each probe optimization effort and initiate probe optimization byassigning lead chemist and coordinating communication between the Vanderbilt chemistrycenter, other MLPCN centers, the MLSMR, and the NIH program administrators.
AIM 2. To effectively manage the integration of activities of medicinal chemistry, informatics andpharmacology components within the Vanderbilt Specialized Chemistry Center.
AIM 3. To coordinate and manage communication and transfer of reagents, data and novel probes tothe scientific community.
AIM 4. To recruit and maintain staff for the proposed MLPCN facility to support and advance theMLPCN goals.
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