This is an application for years 16-20 of NIDA's CTN Florida Node Alliance (FNA).
We aim to build on our past record of success in leading CTN trials in the areas of adolescents, HIV, and interventions for Hispanic substance users; supporting clinical partners and community treatment programs' participation in CTN trials; and leading Node-wide dissemination activities, nationally and internationally. The bidirectional collaboration between scientists and clinical and community partners has been the foundation of our Node and is the mission of the FNA. We propose to expand our reach to a wider spectrum of substance use disorder populations and further engage health care providers, networks, SUD specialty providers, scientists and informatics experts to build the research evidence on new models for mainstream and integrated SUD care and treatment. Our research agenda aims to integrate SBIRT and adolescent drug abuse treatment into primary care settings-- pediatric and school based healthcare centers-- and seeks to improve treatment outcomes in adolescent drug abuse specialty clinics. We also aim to evaluate new and existing models of SUD treatment for substance users at risk for HIV, to test strategies to improve the HIV care continuum among HIV-positive substance users and to test strategies that address co-morbidities associated with HIV including Hepatitis C and depression. To accomplish our research agenda and fulfill the CTN's mission, we bring to the CTN comprehensive health systems such as the Miami VA Healthcare System, the Jackson Health System, Baptist Health System and the University of Miami Health System; and networks such as school-based healthcare centers in Miami-Dade and Colorado, a networks of FQHCs through Health Choice Network; OneFlorida Clinical Research Consortium - a 914 member, practice-based research network (PBRN); the AIDS HealthCare Foundation with 42 HIV care sites, both inpatient and outpatient; and specialty substance use treatment programs, both hospital and community-based, stand alone and as part of comprehensive health systems. Organizations included overwhelmingly have EHRs which can be modified to add NIDA Common Data Elements and that will facilitate point-of-care trials. The FNA, together with the CTN Southern Consortium, bring to the CTN the resources and tools of the CTSA National Consortium.

Public Health Relevance

Our research infrastructure supports the development and implementation of clinical trials to answer a broad spectrum of translational research questions across a wide variety of treatment settings and diverse patient populations. Dissemination partners facilitate training in evidence- based treatments in our service areas.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Clinical Research Cooperative Agreements - Single Project (UG1)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1-JXR-D (11))
Program Officer
Dobbins, Ronald
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Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Miami School of Medicine
Public Health & Prev Medicine
Schools of Medicine
Coral Gables
United States
Zip Code
Winhusen, Theresa; Feaster, Daniel J; Duan, Rui et al. (2017) Baseline Cigarette Smoking Status as a Predictor of Virologic Suppression and CD4 Cell Count During One-Year Follow-Up in Substance Users with Uncontrolled HIV Infection. AIDS Behav :
Stitzer, Maxine; Matheson, Tim; Cunningham, Colin et al. (2017) Enhancing patient navigation to improve intervention session attendance and viral load suppression of persons with HIV and substance use: a secondary post hoc analysis of the Project HOPE study. Addict Sci Clin Pract 12:16
Stitzer, Maxine; Calsyn, Donald; Matheson, Timothy et al. (2017) Development of a Multi-Target Contingency Management Intervention for HIV Positive Substance Users. J Subst Abuse Treat 72:66-71
Hernández, Diana; Feaster, Daniel J; Gooden, Lauren et al. (2016) Self-Reported HIV and HCV Screening Rates and Serostatus Among Substance Abuse Treatment Patients. AIDS Behav 20:204-14
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Alcaide, Maria L; Feaster, Daniel J; Duan, Rui et al. (2016) The incidence of Trichomonas vaginalis infection in women attending nine sexually transmitted diseases clinics in the USA. Sex Transm Infect 92:58-62
Murphy, Sean M; Campbell, Aimee N C; Ghitza, Udi E et al. (2016) Cost-effectiveness of an internet-delivered treatment for substance abuse: Data from a multisite randomized controlled trial. Drug Alcohol Depend 161:119-26
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Metsch, Lisa R; Feaster, Daniel J; Gooden, Lauren et al. (2016) Effect of Patient Navigation With or Without Financial Incentives on Viral Suppression Among Hospitalized Patients With HIV Infection and Substance Use: A Randomized Clinical Trial. JAMA 316:156-70
Gooden, Lauren; Metsch, Lisa R; Pereyra, Margaret R et al. (2016) Examining the Efficacy of HIV Risk-Reduction Counseling on the Sexual Risk Behaviors of a National Sample of Drug Abuse Treatment Clients: Analysis of Subgroups. AIDS Behav 20:1893-906

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