Contact PD/PI: VERBALIS, JOSEPH G PROJECT ABSTRACT The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated hospital systems and research institutes: MedStar Health and Research Institute (MHRI), Oak Ridge National Laboratory (ORNL), and the Washington, DC Veteran's Affairs Medical Center (DCVAMC).
The specific aims of GHUCCTS are: 1) to improve the infrastructure that supports high quality interdisciplinary clinical and translational research, both via inter-institutional collaborations between all GHUCCTS institutions as well as multicenter clinical trials across the national CTSA consortium, with increasing levels of speed and efficiency, and to develop innovative computational methods to speed and enhance translation; 2) to continue to develop GHUCCTS as a model of inter-institutional collaboration that leverages the strengths and attributes of its diverse participating institutions to evolve GHUCCTS into regional CTSA hub with unique and synergistic strengths; 3) to leverage our location, expertise and the co-leadership of a minority-serving institution to design and implement research that will have a high impact on underserved populations with health disparities, including minorities, people with disabilities, and elderly populations; 4) to design and disseminate vibrant and innovative educational programs at multiple levels (undergraduate, medical school, graduate, study coordinators, research nurses, and junior faculty) that promote team science and provides the highest quality of career development training for the clinical and translational investigators of the future; and 5) to both draw from and contribute to the collective efforts of the national CTSA consortium to advance each of the Strategic Goals of GHUCCTS, the National Center for Advancing Translational Science (NCATS), and the CTSA national consortium. The integration of multiple clinical and translational resources across the diverse GHUCCTS institutions will be accompanied by a strong research education, training, and career development program that will train a new generation of clinical and translational researchers. Our innovative approaches to collaboration and interdisciplinary research involving multiple major research-intensive institutions of our region, in collaboration with the national CTSA network, will ensure that our institutions and our community in the Washington, DC area benefit maximally from the generation and application of new discoveries in clinical and translational science. Project Summary/Abstract Page 124 Contact PD/PI: VERBALIS, JOSEPH G

Public Health Relevance

The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a partnership of Georgetown University, Howard University, MedStar Health Research Institute, the Washington DC Veterans Administration Medical Center, and Oak Ridge National Laboratory. Through an innovative collaboration among multiple major research-intensive institutions of our region, GHUCCTS will transform and advance the research and training enterprise in the greater Washington DC region, and will accelerate the translation of scientific discoveries into improved patient care and public health to ensure that our communities in the Washington, DC area benefit maximally from the generation and application of new discoveries in clinical and translational science. Project Narrative Page 125

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
1UL1TR001409-01
Application #
9084738
Study Section
Special Emphasis Panel (ZTR1-SRC (99))
Program Officer
Brazhnik, Olga
Project Start
2015-08-28
Project End
2020-03-31
Budget Start
2015-08-28
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$5,238,330
Indirect Cost
$915,749
Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Fretts, Amanda M; Mete, Mihriye; Howard, Barbara V et al. (2018) Physical activity and telomere length in American Indians: the Strong Heart Study. Eur J Epidemiol 33:497-500
Scott, Rachel K; Crochet, Stacia; Huang, Chun-Chih (2018) Universal Rapid Human Immunodeficiency Virus Screening at Delivery: A Cost-Effectiveness Analysis. Infect Dis Obstet Gynecol 2018:6024698
Beyene, Desta A; Naab, Tammey J; Kanarek, Norma F et al. (2018) Differential expression of Annexin 2, SPINK1, and Hsp60 predict progression of prostate cancer through bifurcated WHO Gleason score categories in African American men. Prostate 78:801-811
Sandberg, Kathryn; Wright, Stephen P; Umans, Jason G (2018) Activity Tracking's Newest Companion: Pulse Wave Velocity. Hypertension 72:294-295
Shanmugam, Victoria K; Mulani, Shaunak; McNish, Sean et al. (2018) Longitudinal observational study of hidradenitis suppurativa: impact of surgical intervention with adjunctive biologic therapy. Int J Dermatol 57:62-69
Bock, Cathryn H; Jay, Allison M; Dyson, Gregory et al. (2018) The effect of genetic variants on the relationship between statins and breast cancer in postmenopausal women in the Women's Health Initiative observational study. Breast Cancer Res Treat 167:741-749
Kahkoska, Anna R; Shay, Christina M; Couch, Sarah C et al. (2018) Sociodemographic associations of longitudinal adiposity in youth with type 1 diabetes. Pediatr Diabetes 19:1429-1440
Klein, Pavel; Dingledine, Raymond; Aronica, Eleonora et al. (2018) Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia 59:37-66
DiEuliis, Diane; Giordano, James (2018) Gene editing using CRISPR/Cas9: implications for dual-use and biosecurity. Protein Cell 9:239-240
Tanner, Julie-Anne; Henderson, Jeffrey A; Buchwald, Dedra et al. (2018) Relationships Between Smoking Behaviors and Cotinine Levels Among Two American Indian Populations With Distinct Smoking Patterns. Nicotine Tob Res 20:466-473

Showing the most recent 10 out of 288 publications