The success of genetic epidemiology lies in replication of results. To that end, this project draws on the AGES-Reykjavik Study and Health, Aging, and Body Composition Study, both of which have been involved in candidate gene studies and will soon complete genome-wide association studies. The studies share several phenotypes in common - measurement of adipose tissue, muscle area, muscle density, measures of grip and quadricep strength, and assessment of physical functioning. If assoications are replicated in these two studies, we will work with consortia of other epidemiology studies to further reinforce (or refute) our findings.
| Day, Felix R (see original citation for additional authors) (2017) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet 49:834-841 |
| Haraldsdottir, Alfheidur; Torfadottir, Johanna E; Valdimarsdottir, Unnur A et al. (2016) Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women. Public Health Nutr 19:318-25 |
| Rossi, Andrea; Zoico, Elena; Goodpaster, Bret H et al. (2010) Quantification of intermuscular adipose tissue in the erector spinae muscle by MRI: agreement with histological evaluation. Obesity (Silver Spring) 18:2379-84 |
| Eiriksdottir, G; Smith, A V; Aspelund, T et al. (2009) The interaction of adiposity with the CRP gene affects CRP levels: age, gene/environment susceptibilty-Reykjavik study. Int J Obes (Lond) 33:267-72 |
