This study has completed and published the second portion of a three part FDG PET study of Tourette Syndrome. We completed and analyzed an H20-15 PET activation study of developmental stuttering, which demonstrated the differences in cerebral activation patterns for speech and language. We also completed and analyzed the following H20-15 PET studies, presently being prepared for publication: a. Functional Elements of Motor Speech; b. Propositional vs. Automatic Speech; c. Prosody and Melody in Speech; d. American Sign Language vs. English; e. Male/Female Differences in Speech and Language. We are continuing an H20-15 PET activation study in Spasmodic Dysphonia, which compares task specific cerebral activity pre- and post-treatment with botulinum toxin. We are also continuing fMRI studies in language and visual perception in deaf and hearing subjects and we developed image processing and analytic techniques for functional neuroimaging studies. We derived methods to: a. determine the contribution of physiological or behavioral signals to PET images; b. segment and extract regionally defined difference scores; c. automatically extract raw values from normalized images; d. develop modified LISREL (structural equation modeling) techniques to analyze regional interrelationship in the brain.
| Meltzer, Jed A; Wagage, Suraji; Ryder, Jennifer et al. (2013) Adaptive significance of right hemisphere activation in aphasic language comprehension. Neuropsychologia 51:1248-59 |
| Horovitz, Silvina G; Braun, Allen R; Carr, Walter S et al. (2009) Decoupling of the brain's default mode network during deep sleep. Proc Natl Acad Sci U S A 106:11376-81 |
| Limb, Charles; Molloy, Anne; Jiradejvong, Patpong et al. (2009) Auditory Cortical Activity During Cochlear Implant-Mediated Perception of Spoken Language, Melody, and Rhythm. J Assoc Res Otolaryngol : |
| Bavelier, D; Newman, A J; Mukherjee, M et al. (2008) Encoding, rehearsal, and recall in signers and speakers: shared network but differential engagement. Cereb Cortex 18:2263-74 |
| Picchioni, Dante; Fukunaga, Masaki; Carr, Walter S et al. (2008) fMRI differences between early and late stage-1 sleep. Neurosci Lett 441:81-5 |
| Fukunaga, Masaki; Horovitz, Silvina G; de Zwart, Jacco A et al. (2008) Metabolic origin of BOLD signal fluctuations in the absence of stimuli. J Cereb Blood Flow Metab 28:1377-87 |
| Braun, Allen; McArdle, Joe; Jones, Jennifer et al. (2008) Tune deafness: processing melodic errors outside of conscious awareness as reflected by components of the auditory ERP. PLoS ONE 3:e2349 |
| Limb, Charles J; Braun, Allen R (2008) Neural substrates of spontaneous musical performance: an FMRI study of jazz improvisation. PLoS ONE 3:e1679 |
| Solomon, Jeffrey; Raymont, Vanessa; Braun, Allen et al. (2007) User-friendly software for the analysis of brain lesions (ABLe). Comput Methods Programs Biomed 86:245-54 |
| Corina, David; Chiu, Yi-Shiuan; Knapp, Heather et al. (2007) Neural correlates of human action observation in hearing and deaf subjects. Brain Res 1152:111-29 |
Showing the most recent 10 out of 29 publications
