The Section on Clinical Assessment and Treatment Evaluation (CATE) is responsible for the care of each patient who is admitted to the NIAAA inpatient and outpatient program. Each participant receives a thorough history and physical examination as well as an extensive laboratory evaluation to assess their general state of health. Additional tests and procedures are ordered when clinically indicated. CATE is responsible for the state of the art treatment program designed for individuals with alcohol dependence as well as co-morbid disorders frequently associated with alcoholism. Participants are obtained from advertisements as well as from referrals from community hospitals, county treatment facilities, and Military/Government establishments. Inquiries are answered promptly by CATE social workers and provide a large data base of candidates from which to select prospective participants for research protocols. Recruitment is protocol-driven and is frequently aimed at specific patient populations such as non-treatment seeking heavy drinkers, anxious alcoholics, and alcoholics with a history of aggression or post traumatic stress disorder. Once a participant is admitted to the program, the participant meets with their primary nurse from the 1SE Adult Behavioral Healthcare Unit nursing staff and their physician on a regular basis to facilitate their recovery. The average inpatient stay is three weeks but the duration is variable depending on an individuals participation in the protocols. During their stay, multiple treatment approaches are offered to the participants including group and individual formats. Groups employing motivational and cognitive approaches are conducted on a daily basis. Family therapy is available several times per week for individuals who wish to participate. Individuals are given the opportunity to attend support groups such as AA or rational recovery during their inpatient hospitalization. Following hospitalization, patients are encouraged to participate in the NIAAA outpatient program which incorporates medication management as well as individual and group therapies. Training and Natural History protocol serves as the platform to evaluate and follow patients participating in the NIAAA inpatient and outpatient programs. It provides the mechanism for CATE to collect clinical and standardized core descriptive data on all participants. In addition, CATE maintains a comprehensive database for the entire NIAAA research candidate cohort. Participant recruitment is ongoing.

Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2009
Total Cost
$1,008,312
Indirect Cost
Name
National Institute on Alcohol Abuse and Alcoholism
Department
Type
DUNS #
City
State
Country
Zip Code
Vatsalya, Vatsalya; Song, Ming; Schwandt, Melanie L et al. (2016) Effects of Sex, Drinking History, and Omega-3 and Omega-6 Fatty Acids Dysregulation on the Onset of Liver Injury in Very Heavy Drinking Alcohol-Dependent Patients. Alcohol Clin Exp Res 40:2085-2093
Hirvonen, J; Zanotti-Fregonara, P; Umhau, J C et al. (2013) Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography. Mol Psychiatry 18:916-21
Umhau, John C; George, David T; Heaney, Robert P et al. (2013) Low vitamin D status and suicide: a case-control study of active duty military service members. PLoS One 8:e51543
Schwandt, Melanie L; Heilig, Markus; Hommer, Daniel W et al. (2013) Childhood trauma exposure and alcohol dependence severity in adulthood: mediation by emotional abuse severity and neuroticism. Alcohol Clin Exp Res 37:984-92
Umhau, John C; Trandem, Karysse; Shah, Mohsin et al. (2012) The physician's unique role in preventing violence: a neglected opportunity? BMC Med 10:146
Huang, Ming-Chyi; Schwandt, Melanie L; Ramchandani, Vijay A et al. (2012) Impact of multiple types of childhood trauma exposure on risk of psychiatric comorbidity among alcoholic inpatients. Alcohol Clin Exp Res 36:1099-107
Snell, Lawrence D; Ramchandani, Vijay A; Saba, Laura et al. (2012) The biometric measurement of alcohol consumption. Alcohol Clin Exp Res 36:332-41
Zhang, Lishu; Kerich, Mike; Schwandt, Melanie L et al. (2011) Smaller right amygdala in Caucasian alcohol-dependent male patients with a history of intimate partner violence: a volumetric imaging study. Addict Biol :
Umhau, John C; Schwandt, Melanie L; Usala, Julie et al. (2011) Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. Neuropsychopharmacology 36:1178-86
Ramchandani, V A; Umhau, J; Pavon, F J et al. (2011) A genetic determinant of the striatal dopamine response to alcohol in men. Mol Psychiatry 16:809-17

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