In fiscal year 2012, we continued to follow up with the results obtained with our microarray data. In 2010, the protocol was amended to allow us to treat healthy volunteers with doxycycline to obtain additional biopsies. In 2011, we completed treatment of additional healthy volunteers. In 2012, we completed the analysis of immunohistochemical staining of additional biopsies obtained from healthy volunteers treated with doxycycline. We also sent stored serum from the initial healthy volunteers to evaluate for doxycycline serum levels, which have recently been completed.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIABC010914-05
Application #
8552888
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2012
Total Cost
$39,416
Indirect Cost
Name
National Cancer Institute Division of Basic Sciences
Department
Type
DUNS #
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State
Country
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