Ongoing and planned studies include evaluation of populations exposed to benzene, chlorinated solvents, organochlorines, disinfection byproducts. polycyclic aromatic hydrocarbons, arsenic, formaldehyde, diesel exhaust, coal combustion products, and selected pesticides. On-going case-control studies of stomach, esophagus, brain, bladder, renal cell, thyroid, prostate and breast cancer, NHL, and benzene-induced hematotoxicity and hematologic malignancies and cohort studies of women in China and agricultural workers in the United States are evaluating a range of potential genetic risk factors and their interaction with occupational and environmental exposures. Many of these studies are also collecting tumor samples for future molecular analyses.

National Institute of Health (NIH)
National Cancer Institute (NCI)
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Division of Cancer Epidemiology and Genetics
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Lu, Sixin S; Grigoryan, Hasmik; Edmands, William M B et al. (2017) Profiling the Serum Albumin Cys34 Adductome of Solid Fuel Users in Xuanwei and Fuyuan, China. Environ Sci Technol 51:46-57
GBD 2015 Healthcare Access and Quality Collaborators. Electronic address:; GBD 2015 Healthcare Access and Quality Collaborators (2017) Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015. Lancet 390:231-266
Seow, Wei Jie; Matsuo, Keitaro; Hsiung, Chao Agnes et al. (2017) Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations. Hum Mol Genet 26:454-465
Wong, Jason Y; Bassig, Bryan A; Vermeulen, Roel et al. (2017) Sleep Duration across the Adult Lifecourse and Risk of Lung Cancer Mortality: A Cohort Study in Xuanwei, China. Cancer Prev Res (Phila) 10:327-336
Seow, Wei Jie; Lan, Qing (2016) Domestic incense use and lung cancer in Asia: a review. Rev Environ Health 31:155-8
Wang, Zhaoming; Seow, Wei Jie; Shiraishi, Kouya et al. (2016) Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. Hum Mol Genet 25:620-9
Espejo-Herrera, Nadia; Cantor, Kenneth P; Malats, Nuria et al. (2015) Nitrate in drinking water and bladder cancer risk in Spain. Environ Res 137:299-307
Wang, Teresa W; Vermeulen, Roel C H; Hu, Wei et al. (2015) Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal. Carcinogenesis 36:1494-501
Lan, Qing; Smith, Martyn T; Tang, Xiaojiang et al. (2015) Chromosome-wide aneuploidy study of cultured circulating myeloid progenitor cells from workers occupationally exposed to formaldehyde. Carcinogenesis 36:160-7
Seow, Wei Jie; Hu, Wei; Vermeulen, Roel et al. (2014) Household air pollution and lung cancer in China: a review of studies in Xuanwei. Chin J Cancer 33:471-5

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