We investigate dietary factors in cohort studies and nutrition related biomarkers in nested case controls studies within the PLCO screeening trial cohort. The dietary factors have included glycemic index and folate. Biomarkers studies have included vitamin D, and insulin like growth factors and insulin resistance factors. PLCO has also participated in the VDPP. Thus far the studies for vitamin D, the Vitamin D Pooling Project for Rare Cancers , the IGF-1 axis biomarker studies and the folate and glycemic index dietary intake studies have completed and published.

National Institute of Health (NIH)
National Cancer Institute (NCI)
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Division of Cancer Epidemiology and Genetics
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Toriola, Adetunji T; Ziegler, Mark; Li, Yize et al. (2017) Prediagnosis Circulating Insulin-Like Growth Factors and Pancreatic Cancer Survival. Ann Surg Oncol :
Stolzenberg-Solomon, Rachael Z; Newton, Christina C; Silverman, Debra T et al. (2015) Circulating Leptin and Risk of Pancreatic Cancer: A Pooled Analysis From 3 Cohorts. Am J Epidemiol 182:187-97
Piper, Marina R; Freedman, D Michal; Robien, Kim et al. (2015) Vitamin D-binding protein and pancreatic cancer: a nested case-control study. Am J Clin Nutr 101:1206-15
Olson, Sara H; Hsu, Meier; Wiemels, Joseph L et al. (2014) Serum immunoglobulin e and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 23:1414-20
Jacobs, Eric J; Newton, Christina C; Silverman, Debra T et al. (2014) Serum transforming growth factor-?1 and risk of pancreatic cancer in three prospective cohort studies. Cancer Causes Control 25:1083-91
Arem, H; Bobe, G; Sampson, J et al. (2013) Flavonoid intake and risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study Cohort. Br J Cancer 108:1168-72
Brock, Kaye E; Huang, Wen-Yi; Fraser, David R et al. (2011) Diabetes prevalence is associated with serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in US middle-aged Caucasian men and women: a cross-sectional analysis within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Br J Nutr 106:339-44
Douglas, Jason B; Silverman, Debra T; Weinstein, Stephanie J et al. (2011) Serum C-reactive protein and risk of pancreatic cancer in two nested, case-control studies. Cancer Epidemiol Biomarkers Prev 20:359-69
Meinhold, Cari L; Dodd, Kevin W; Jiao, Li et al. (2010) Available carbohydrates, glycemic load, and pancreatic cancer: is there a link? Am J Epidemiol 171:1174-82
Oaks, Brietta M; Dodd, Kevin W; Meinhold, Cari L et al. (2010) Folate intake, post-folic acid grain fortification, and pancreatic cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Am J Clin Nutr 91:449-55

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