We have thus far evaluated 50 donors since the protocol started in 3/2009. All donors who have returned thus far have reported that the kidney donation has been a positive experience. No one thus far has had expressed any sense of regret or concerns regarding care received at the NIH. In some donors, the experience of kidney donation has encouraged them to make healthy life style choices. In many we have thus seen, however, development of weight gain, hypertension, and hyperlipidemia has not been uncommon, as in the general population. We plan to start formal analysis of the medical and psychosocial data within the next 3 months.

Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2010
Total Cost
$77,266
Indirect Cost
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State
Country
Zip Code
Chen, Xinjian; Summers, Ronald M; Cho, Monique et al. (2012) An automatic method for renal cortex segmentation on CT images: evaluation on kidney donors. Acad Radiol 19:562-70
Sharma, Kumar; Ix, Joachim H; Mathew, Anna V et al. (2011) Pirfenidone for diabetic nephropathy. J Am Soc Nephrol 22:1144-51
Cho, Monique E; Kopp, Jeffrey B (2010) Pirfenidone: an anti-fibrotic therapy for progressive kidney disease. Expert Opin Investig Drugs 19:275-83
Cho, M E; Duan, Z; Chamberlain, C E et al. (2010) Cinacalcet improves bone density in post-kidney transplant hyperparathyroidism. Transplant Proc 42:3554-8