The Hematopathology Fellowship has been highly successful in attracting outstanding applicants and in providing them with training in hematopathology, emphasizing outstanding clinical diagnosis, and specialized diagnostic tools including molecular diagnostics and flow cytometry. The fellowship has been ACGME accredited since 2000, and graduating fellows have had a nearly a 100% first time pass rate on the accrediting examination given by the American Board of Pathology. Graduating fellows have gone on to establish independent careers in academic medicine, including appointments in recent years at Duke University, Northwestern University Medical Center, Moffit Cancer Center, Children's National Medical Center, University of Chicago, Weill Cornell Medical School), City of Hope National Medical Center, The Mayo Clinic, Memorial Sloan Kettering Cancer Center, Henry Ford Hospital, and the Cleveland Clinic. Four recent graduates have successfully competed for independent NIH RO1 funding. Fellows are encouraged to participate in clinical research; representative first authored publications by trainees over the past year are noted below, and cover a variety of topics in hematopathology .1-7 1. Menon MP, Nicolae A, Meeker H, et al. Primary CNS T-Cell Lymphomas: Clinical, Morphologic, Immunophenotypic and Molecular Analysis. Am J Surg Pathol. in press 2. Xie Y, Pittaluga S, Jaffe ES. The Histological Classification of Diffuse Large B-cell Lymphomas. Seminars in Hematology. 2015;52:57-66. 3. Song JY, Pittaluga S, Dunleavy K, et al. Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations. Am J Surg Pathol. 2015;39:141-156. 4. Nicolae A, Pittaluga S, Abdullah S, et al. EBV positive large B cell lymphomas in young patients: a nodal lymphoma with evidence for a tolerogenic immune environment. Blood. 2015. 5. Lee YS, Filie A, Arthur D, et al. Breast implant-associated anaplastic large cell lymphoma in a patient with Li-Fraumeni syndrome. Histopathology. 2015. 6. Zhao X, Townsley DM, Young NS, et al. Increased Hematogones Mimic B Lymphoblastic Leukemia in Non-Transplant Bone Marrows of Patients Treated for Acquired Aplastic Anemia. Modern Pathology. 2013;26:370a-370a. 7. Flatley E, Chen AI, Zhao XR, et al. Aberrations of MYC Are a Common Event in B-Cell Prolymphocytic Leukemia. American Journal of Clinical Pathology. 2014;142:347-354.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Clinical Training Intramural Research (ZIE)
Project #
1ZIEBC011241-07
Application #
9154391
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Basic Sciences
Department
Type
DUNS #
City
State
Country
Zip Code
Egan, Caoimhe; Jaffe, Elaine S (2018) Non-neoplastic histiocytic and dendritic cell disorders in lymph nodes. Semin Diagn Pathol 35:20-33
Balakrishna, Jayalakshmi P; Bhavsar, Tapan; Nicolae, Alina et al. (2018) Human Herpes Virus 6 (HHV-6)-associated Lymphadenitis: Pitfalls in Diagnosis in Benign and Malignant Settings. Am J Surg Pathol 42:1402-1408
Li, Yiting; Gupta, Gunjan; Molofsky, Ari et al. (2018) B Lymphoblastic Leukemia/Lymphoma With Burkitt-like Morphology and IGH/MYC Rearrangement: Report of 3 Cases in Adult Patients. Am J Surg Pathol 42:269-276
Wang, Huan-You; Jaffe, Elaine S (2018) An anaplastic T-cell lymphoma mimicking classical Hodgkin lymphoma. Blood 131:1262
Nicolae, Alina; Ganapathi, Karthik A; Pham, Trinh Hoc-Tran et al. (2017) EBV-negative Aggressive NK-cell Leukemia/Lymphoma: Clinical, Pathologic, and Genetic Features. Am J Surg Pathol 41:67-74
Balakrishna, Jayalakshmi P; Jaffe, Elaine S (2017) Crystal-storing histiocytosis associated with thymic extranodal marginal zone lymphoma. Blood 130:1683
Pilichowska, Monika; Pittaluga, Stefania; Ferry, Judith A et al. (2017) Clinicopathologic consensus study of gray zone lymphoma with features intermediate between DLBCL and classical HL. Blood Adv 1:2600-2609
Okonkwo, Linda; Jaffe, Elaine S (2017) Intravascular large cell lymphoma of NK/T-cell type, EBV positive. Blood 130:837
Xiao, Wenbin; Chen, Wayne W; Sorbara, Lynn et al. (2016) Hodgkin lymphoma variant of Richter transformation: morphology, Epstein-Barr virus status, clonality, and survival analysis-with comparison to Hodgkin-like lesion. Hum Pathol 55:108-116
Ganapathi, Karthik A; Jobanputra, Vaidehi; Iwamoto, Fabio et al. (2016) The genetic landscape of dural marginal zone lymphomas. Oncotarget :

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