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Goals and Theme of the Community Outreach Educational Core (COEC) The primary goal of the COEC will be to educate residents in the Louisville Metropolitan Area (nine counties in Kentucky...
Asthma is characterized by eosinophilic inflammation of the airways. Interleukin-5 (IL-5) is one of the most important regulators of eosinophil differentiation and function. IL-5 activates eosinophils by stimulating a number...
Project 3: Estimating Risk of Ovarian Cancer Ovarian cancer afflicts approximately 26,000 US women per year. More than 70% of these cases will be diagnosed in late stage and the...
The proposed research will further evaluate the mechanisms by which hormones regulate the growth of kidney epithelial cells, and the alterations which occur upon malignant transformation. These studies will be...
Recent advances in design and actuation have led to important improvements in prosthetic limbs. However, these devices lack a means for providing direct sensory feedback, requiring users to infer information...
Over 2.5 million U.S. service members have been deployed to Afghanistan or Iraq war zones since 2002 and, according to reports from the Department of Veterans Affairs, one in every...
Background: Despite medical advances, up to 70% of health outcomes are due to social determinants of health (SDoH) - the conditions in which people live and work that shape whether...
Effective evidence-based clinical practice in the communication sciences and other health professions requires several stages of development from basic science to clinical practice. First, clinical research that generates diagnostic and...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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