Cardiovascular disease (CVD) is a disease of enormous public health significance that leads to the death of nearly one millions Americans each year and acute myocardial infarction is a leading cause of death worldwide. Through polymorphism registry studies, we have identified gene-environment interactions in the EET sythesis and degradation pathways that influence cardiovascular outcomes. We anticipate that the development of these animal models will lead to the novel therapeutic and/or preventative strategies for cardiovascular disease and will greatly facilitate mechanistic studies into the pathogenesis of these disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research and Development Contracts (N01)
Project #
273200700001I-0-27300008-1
Application #
7939364
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
2009
Total Cost
$13,000
Indirect Cost
Name
Xenogen Biosciences
Department
Type
DUNS #
City
Cranbury
State
NJ
Country
United States
Zip Code
08512