The risk of developing Kaposi's sarcoma, non-Hodgkin's lymphoma, cervical dysplasia and other cancers is greatly increased in people who have HIV infection. While recent research developments have presented new opportunities for productive research in the area of HIV-associated malignancies, international collaborations involving US-based investigators and those in developing countries have been limited. The objective of this supplemental program to the UCLA-Fogarty AIRTP (AIDS International Training and Research Programs, Dr. Roger Detels, PI) is to provide research training opportunities in AIDS malignancies for investigators from developing countries, with the aim of enhancing their ability to conduct research in this area. A secondary objective is to enhance the ability of UCLA-based investigators to carry out research in AIDS-associated cancers, much of which is funded by existing grants from the NIH-NCI, by facilitating international interactions that provide access to unique patient populations, resources, or research collaborations. At this time, there are several active international collaborations in the area of HIV-associated malignancies involving UCLA faculty and researchers in Brazil, on topics such as HHV8/KSHV seroprevalence, HPV infection and cervical dysplasia in HIV+ women, and the molecular epidemiology of AIDS-lymphoma. This supplemental program will support both short-term and long-term training visits by investigators (primarily postdoctoral-level) from developing countries to work with appropriate investigators at UCLA. In addition to individualized short and long-term training opportunities, supplemental AITRP funding will be used to give workshops on issues that are relevant to AIDS malignancies research. Visits to foreign countries by UCLA investigators, to develop or maintain collaborations in HIV-associated cancer research by interacting with colleagues or trainees, will be supported. Finally, a limited number of small re-entry seed grants will be provided to select program trainees. Overall, this supplemental program will allow the maintenance and expansion of existing interactions, will help build the capacity of foreign investigators to do AIDS-cancer research, and will enhance the ability of UCLA-based investigators to carry out NIH-sponsored studies in AIDS and cancer.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW000013-13S5
Application #
6311427
Study Section
Special Emphasis Panel (ZAI1-GLM-F (S1))
Program Officer
Mcdermott, Jeanne
Project Start
1998-09-30
Project End
2003-09-29
Budget Start
2000-09-30
Budget End
2001-09-29
Support Year
13
Fiscal Year
2000
Total Cost
$96,702
Indirect Cost
Name
University of California Los Angeles
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Das, Aritra; Detels, Roger; Afifi, Abdelmonem A et al. (2018) Formation and psychometric evaluation of a health-related quality of life instrument for children living with HIV in India. J Health Psychol 23:577-587
Liu, Xing; Baecker, Aileen; Wu, Ming et al. (2018) Interaction between tobacco smoking and hepatitis B virus infection on the risk of liver cancer in a Chinese population. Int J Cancer 142:1560-1567
Das, Aritra; Detels, Roger; Afifi, Abdelmonem A et al. (2017) Health-related quality of life (HRQoL) and its correlates among community-recruited children living with HIV and uninfected children born to HIV-infected parents in West Bengal, India. Qual Life Res 26:2171-2180
Bonavida, B; Chouaib, S (2017) Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance. Ann Oncol 28:457-467
Das, Aritra; Detels, Roger; Javanbakht, Marjan et al. (2017) Living with HIV in West Bengal, India: perceptions of infected children and their caregivers. AIDS Care 29:800-806
Bonham, Luke W; Geier, Ethan G; Fan, Chun C et al. (2016) Age-dependent effects of APOE ?4 in preclinical Alzheimer's disease. Ann Clin Transl Neurol 3:668-77
Das, A; Detels, R; Javanbakht, M et al. (2016) Issues around childhood disclosure of HIV status - findings from a qualitative study in West Bengal, India. Child Care Health Dev 42:553-64
Chotivichien, Saipin; Arab, Lenore; Prasithsirikul, Wisit et al. (2016) Effect of nutritional counseling on low-density lipoprotein cholesterol among Thai HIV-infected adults receiving antiretroviral therapy. AIDS Care 28:257-65
Nguyen, Thuong Vu; Van Khuu, Nghia; Nguyen, Phuc Duy et al. (2016) Sociodemographic Factors, Sexual Behaviors, and Alcohol and Recreational Drug Use Associated with HIV Among Men Who Have Sex with Men in Southern Vietnam. AIDS Behav 20:2357-2371
Hines, Lindsay J; Miller, Eric N; Hinkin, Charles H et al. (2016) Cortical brain atrophy and intra-individual variability in neuropsychological test performance in HIV disease. Brain Imaging Behav 10:640-51

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