This is the first competitive renewal application for the UNC AIDS International Training and Research Program. We propose to continue to provide training in three countries: The Peoples Republic of China, Malawi and Cameroon. Investigators at UNC have worked in China since 1979, Malawi since 1989, and Cameroon since 1998. The UNC AITRP has embraced several guiding principles. First, we have tried to use training to build strong ties to key in-country organizations. Second, we have selected training opportunities that build on funded research projects that can bridge all the strengths of UNC. Wherever possible we """"""""overlap"""""""" basic, clinical and epidemiological training and research so as to build critical mass. Third, we have used the Fogarty training to embrace and promote international research networks including the HIV Prevention Trials Network (HPTN, China, Malawi), the HIV Vaccine Network (HIVNET, China), the AIDS Clinical Trials Group (ACTG, Malawi), WHO STI Initiative (China), and Center for Intemational Prevention of AIDS (CIPRA, China); we have worked to help secure UNAIDS Global Funds and consider the potential impact of support by the Global Fund. Fourth, we have developed critical south-south and international collaborations to facilitate training and ongoing research opportunities including the Thai Red Cross, the University of Witwatersrand, the London School of Hygiene and Tropical Medicine, and the University of Chicago. Fifth, we have looked for opportunities for evolution and innovation including formation of new collaborations, development of unique reentry strategies, and application of novel technologies relevant to the countries involved. Sixth, we are committed to decentralized and in-country leadership. The UNC Fogarty training is designed to react specifically to recent country assessments, ongoing funded research projects, and the contribution of the Global Fund. The trainees should find themselves in the center of critical activities, with skill sets in demand. The UNC Program takes a cross-cutting approach to training, with equal emphasis on public health, behavioral, basic and clinical research. This renewal Application embraces short, medium and long-term training opportunities balanced between the opprtunities and needs of each country. Degree training has been emphasized in Malawi and Cameroon, including support for a new public health school in Malawi.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW001039-09S2
Application #
7497200
Study Section
Special Emphasis Panel (ZRG1-ICP-3 (02))
Program Officer
Mcdermott, Jeanne
Project Start
1998-09-30
Project End
2009-05-31
Budget Start
2007-06-01
Budget End
2008-05-31
Support Year
9
Fiscal Year
2007
Total Cost
$100,000
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Ewing, Alexander C; Ellington, Sascha R; Wiener, Jeffrey B et al. (2018) Predictors of Perinatal HIV Transmission Among Women Without Prior Antiretroviral Therapy in a Resource-Limited Setting: The BAN Study. Pediatr Infect Dis J :
Hampel, Daniela; Shahab-Ferdows, Setareh; Gertz, Erik et al. (2018) The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers. Matern Child Nutr 14:e12503
Chevalier, Michelle S; King, Caroline C; Ellington, Sascha et al. (2017) Maternal and neonatal outcomes among women with HIV infection and their infants in Malawi. Int J Gynaecol Obstet 137:282-289
Ewing, Alexander C; King, Caroline C; Wiener, Jeffrey B et al. (2017) Effects of concurrent exposure to antiretrovirals and cotrimoxazole prophylaxis among HIV-exposed, uninfected infants. AIDS 31:2455-2463
Zadrozny, Sabrina; Westreich, Daniel; Hudgens, Michael G et al. (2017) Effect of Postnatal HIV Treatment on Clinical Mastitis and Breast Inflammation in HIV-Infected Breast-feeding Women. Paediatr Perinat Epidemiol 31:134-143
Chagomerana, Maganizo B; Miller, William C; Pence, Brian W et al. (2017) PMTCT Option B+ Does Not Increase Preterm Birth Risk and May Prevent Extreme Prematurity: A Retrospective Cohort Study in Malawi. J Acquir Immune Defic Syndr 74:367-374
Davis, Nicole L; Miller, William C; Hudgens, Michael G et al. (2016) Maternal and Breast Milk Viral Load: Impacts of Adherence on Peri-Partum HIV Infections Averted - the BAN Study. J Acquir Immune Defic Syndr :
Hampel, Daniela; Shahab-Ferdows, Setareh; Adair, Linda S et al. (2016) Thiamin and Riboflavin in Human Milk: Effects of Lipid-Based Nutrient Supplementation and Stage of Lactation on Vitamer Secretion and Contributions to Total Vitamin Content. PLoS One 11:e0149479
Davis, Nicole L; Miller, William C; Hudgens, Michael G et al. (2016) Maternal and Breastmilk Viral Load: Impacts of Adherence on Peripartum HIV Infections Averted-The Breastfeeding, Antiretrovirals, and Nutrition Study. J Acquir Immune Defic Syndr 73:572-580
Sellers, Christopher J; Lee, Hana; Chasela, Charles et al. (2015) Reducing lost to follow-up in a large clinical trial of prevention of mother-to-child transmission of HIV: the Breastfeeding, Antiretrovirals and Nutrition study experience. Clin Trials 12:156-65

Showing the most recent 10 out of 101 publications