This international AIDS research training program has India as its major country of focus and Rwanda and Bangladesh as minor countries. Our goal is research capacity-building in these countries in the areas of HIV/AIDS, tuberculosis and fungal pathogens of AIDS. To this end, we propose to train scientists from these countries in critical biomedical, epidemiological and behavioral research methodologies. Accessory training in blood safety and clinical research is also provided. Our training models include short, medium and long- term training. Short-term training will be in-country (to be held mostly in India but attended by trainees in all three countries and sometimes in Rwanda for trainees in that country) via 10-day workshops aimed at specialized topics aimed at training clinicians and basic researchers in specific HIV/AIDS areas. Medium- term training for 3-6 months is our core training model involving training of graduate students registered for thesis research in AIDS topics in India or Bangladesh visiting Albert Einstein for research involving (but not limited to): Characterization of local subtypes of HIV; Basis for possible differential incidence of dementia in AIDS; Drug resistance in HIV and its detection; Developing AIDS prevention methods and the evaluation of their efficacy; Epidemiological studies on attitudes of women to HAART; Development of diagnostics for C. neoformans and Candida sp.; Molecular biology and pathogenesis of fungal opportunistic pathogens of AIDS; Rapid, inexpensive phage-based detection methods for M. tuberculosis and Genetic approaches to study role of M. tuberculosis genes. Our long-term training consists of two components: a Master's degree in Clinical Research Training Program (CRTP) and Post-doctoral research training both in AIDS research. While the short-term and the long-term training covers all three countries, the medium-term US training is initially focused on India and Bangladesh. For Rwanda, we also propose in-country training in epidemiology. An important element of our training plan is ensuring the return of the trainees to their home countries by training graduate students in mid-stream which ensures their return and sharing of expertise, selecting long- term trainees with prior permanent positions as well as assisting them find positions in biomedical research organizations as well as via Advanced in-country research project support for eligible individuals.

National Institute of Health (NIH)
Fogarty International Center (FIC)
International Research Training Grants (D43)
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Special Emphasis Panel (ZRG1-ICP2-B (51))
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Mcdermott, Jeanne
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Albert Einstein College of Medicine
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Adedimeji, Adebola A; Hoover, Donald R; Shi, Qiuhu et al. (2015) Sexual Behavior and Risk Practices of HIV Positive and HIV Negative Rwandan Women. AIDS Behav 19:1366-78
Dusingize, Jean Claude; Hoover, Donald R; Shi, Qiuhu et al. (2015) Association of Abnormal Liver Function Parameters with HIV Serostatus and CD4 Count in Antiretroviral-Naive Rwandan Women. AIDS Res Hum Retroviruses 31:723-30
Sinayobye, Jean d'Amour; Hoover, Donald R; Shi, Qiuhu et al. (2015) Prevalence of shingles and its association with PTSD among HIV-infected women in Rwanda. BMJ Open 5:e005506
Mutimura, Eugene; Hoover, Donald R; Shi, Qiuhu et al. (2015) Insulin resistance change and antiretroviral therapy exposure in HIV-infected and uninfected Rwandan women: a longitudinal analysis. PLoS One 10:e0123936
Neogi, Ujjwal; Rao, Shwetha D; Bontell, Irene et al. (2014) Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients. AIDS 28:2319-22
Tumusiime, David K; Musabeyezu, Emmanuel; Mutimurah, Eugene et al. (2014) Over-reported peripheral neuropathy symptoms in a cohort of HIV infected and uninfected Rwandan women: the need for validated locally appropriate questionnaires. Afr Health Sci 14:460-7
Hanna, Luke Elizabeth; Neogi, Ujjwal; Ranga, Udaykumar et al. (2014) Phylogenetic characterization of six full-length HIV-1 subtype C molecular clones from three patients: identification of rare subtype C strains containing two NF-?B motifs in the long terminal repeat. AIDS Res Hum Retroviruses 30:586-91
Cooperman, Nina A; Shastri, Jayanthi S; Shastri, Aditi et al. (2014) HIV prevalence, risk behavior, knowledge, and beliefs among women seeking care at a sexually transmitted infection clinic in Mumbai, India. Health Care Women Int 35:1133-47
Benning, Lorie; Golub, Elizabeth T; Anastos, Kathryn et al. (2014) Comparison of lower genital tract microbiota in HIV-infected and uninfected women from Rwanda and the US. PLoS One 9:e96844
Rao, Vasudev R; Neogi, Ujjwal; Eugenin, Eliseo et al. (2014) The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates. PLoS One 9:e107074

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