Uganda faces problems of rapid population growth and low contraceptive prevalence, as well as reproductive health problems including sexually transmitted diseases, genital tract infections, and a generalized HIV epidemic. The Institute of Public Health (IPH) and Department of Population Studies (DPS) at Makerere University have collaborated with the Department of Population and Family Health Sciences and the NIH- funded Population Center at Johns Hopkins and Columbia Universities, collaborated on the Rakai Project, and conducted population-based epidemiologic, demographic, behavioral and biomedical studies in rural Rakai District, southwestern Uganda. The Rakai Project currently has several NIH grants (RO1s and UO1s), and has benefitted from Fogarty Foundation funding. This proposal builds on our prior Fogarty support to continue builds Population and Health research and training at Makerere University. Three previous Fogarty Masters graduates will complete doctoral training, and 3 new candidates will complete masters training at JHU. These graduates will develop Advanced Research Training proposals on their return to Uganda. We also propose 7 short-term trainees (5 in population/reproductive health, and 2 in laboratory methods). On their return, trainees will rotate through the Rakai Project field site and other field projects, to obtain practical experience. There will be 8 postdoctoral Fellows (3 research Fellows, 3 teaching Fellows to work on training and curriculum development for Makerere, and 2 clinical Fellows in reproductive health). We propose 5 in-country workshops to develop research training and curriculum development for Makerere, and a Conference in Year 5 to disseminate research findings. The program will be coordinated with other JHU Fogarty programs, the JHU Gates Institute (which will provide cost-sharing), and the JHU Mellon Distance Learning Program to facilitate internet access and transfer of training materials. The US and Uganda-based training, research and curriculum development will enhance development of and coordination between DPS and IPH, to provide an integrated long-term, self-replicating program of Population and Reproductive Health in Uganda. The goal is to establish a critical mass of researchers and trainers in Uganda who will sustain training programs submit high quality NIH research proposals, and conduct independent research. Ultimately, we see Uganda and Makerere University providing a resource for regional research training in Africa.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW001508-02
Application #
6395014
Study Section
Special Emphasis Panel (ZHD1-DRG-S (04))
Program Officer
Mcdermott, Jeanne
Project Start
2000-09-29
Project End
2005-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
2
Fiscal Year
2001
Total Cost
$209,801
Indirect Cost
Name
Johns Hopkins University
Department
Miscellaneous
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Nakigozi, Gertrude; Makumbi, Fredrick E; Bwanika, John B et al. (2015) Impact of Patient-Selected Care Buddies on Adherence to HIV Care, Disease Progression, and Conduct of Daily Life Among Pre-antiretroviral HIV-Infected Patients in Rakai, Uganda: A Randomized Controlled Trial. J Acquir Immune Defic Syndr 70:75-82
Wagman, Jennifer A; Gray, Ronald H; Campbell, Jacquelyn C et al. (2015) Effectiveness of an integrated intimate partner violence and HIV prevention intervention in Rakai, Uganda: analysis of an intervention in an existing cluster randomised cohort. Lancet Glob Health 3:e23-33
Kairania, Robert; Gray, Ronald H; Wawer, Maria J et al. (2015) Intimate partner violence and communication of HIV diagnosis in Rakai, Uganda. Soc Work Public Health 30:272-81
Grabowski, Mary K; Gray, Ronald H; Serwadda, David et al. (2014) High-risk human papillomavirus viral load and persistence among heterosexual HIV-negative and HIV-positive men. Sex Transm Infect 90:337-43
Tobian, Aaron A R; Gaydos, Charlotte; Gray, Ronald H et al. (2014) Male circumcision and Mycoplasma genitalium infection in female partners: a randomised trial in Rakai, Uganda. Sex Transm Infect 90:150-4
Tobian, Aaron A R; Grabowski, Mary K; Kigozi, Godfrey et al. (2013) Human papillomavirus clearance among males is associated with HIV acquisition and increased dendritic cell density in the foreskin. J Infect Dis 207:1713-22
Wilson, Lauren E; Gravitt, Patti; Tobian, Aaron A R et al. (2013) Male circumcision reduces penile high-risk human papillomavirus viral load in a randomised clinical trial in Rakai, Uganda. Sex Transm Infect 89:262-6
Tobian, Aaron A R; Grabowski, Mary K; Kigozi, Godfrey et al. (2013) High-risk human papillomavirus prevalence is associated with HIV infection among heterosexual men in Rakai, Uganda. Sex Transm Infect 89:122-7
Ssekubugu, Robert; Leontsini, Elli; Wawer, Maria J et al. (2013) Contextual barriers and motivators to adult male medical circumcision in Rakai, Uganda. Qual Health Res 23:795-804
Davis, Mitzie-Ann; Gray, Ronald H; Grabowski, Mary K et al. (2013) Male circumcision decreases high-risk human papillomavirus viral load in female partners: a randomized trial in Rakai, Uganda. Int J Cancer 133:1247-52

Showing the most recent 10 out of 29 publications